Dicorate ER 750 mg Tablet

Dicorate ER 750 mg Tablet contains 750 mg of divalproex in each extended-release tablet. It belongs to the anticonvulsant and mood-stabilizing drug class, and this product is used to help prevent migraine headaches in appropriate patients. Because it is an extended-release tablet, Dicorate ER 750 mg Tablet is designed to release medicine gradually over time.

How it works: Divalproex helps calm overactive electrical activity in the nervous system and may reduce the brain signals involved in migraine attacks. As an extended-release tablet, Dicorate ER 750 mg Tablet releases divalproex slowly so medicine levels stay steadier through the day.

Dicorate ER 750 mg Tablet is a higher-strength option compared with Dicorate ER 125 mg Tablet, Dicorate ER 250 mg Tablet, and Dicorate ER 500 mg Tablet, so it is usually chosen for patients who have already been assessed and need a larger per-tablet amount. It may simplify dosing for someone taking a prescribed total daily dose that is better matched by 750 mg tablets, rather than using several lower-strength tablets. This strength is not meant to be started casually without a doctor’s plan.

• Prevention of migraine headaches
• Long-term migraine management when prescribed
• Extended-release divalproex therapy as directed by a clinician

• Swallow Dicorate ER 750 mg Tablet whole with water; do not crush, chew, or split it.
• Take it exactly at the same time each day if your doctor prescribes daily use.
• It may be taken with food or after a meal if stomach upset occurs.
• Do not change to a different divalproex product or strength unless your prescriber tells you to.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.
• Follow the exact tablet count prescribed, since this 750 mg strength is a higher-dose tablet.

Each Dicorate ER 750 mg Tablet provides 750 mg of divalproex in one extended-release tablet. How often it is taken can vary based on the migraine prevention plan your doctor chooses, and the total daily dose may be divided or adjusted based on your response and tolerance. Do not take more than prescribed; your clinician determines the correct daily dose and any maximum for you.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Divalproex may include:

• Nausea
• Sleepiness or drowsiness
• Dizziness
• Tremor
• Stomach pain
• Weight gain
• Hair thinning

• Dicorate ER 750 mg Tablet is a higher-strength tablet, so only take it under a prescriber’s direction and do not self-adjust the dose.
• Do not crush, chew, or split the extended-release tablet, because that can change how quickly divalproex is released.
• Alcohol can worsen drowsiness and dizziness and should be avoided unless your doctor says otherwise.
• Use extra caution if you have liver disease, pancreas problems, bleeding disorders, or a history of low platelets.
• This medicine can cause sleepiness or slower reaction time, so be careful driving or using machinery until you know how it affects you.
• Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding, because divalproex has important safety concerns in pregnancy.
• Report rash, unusual bruising, severe abdominal pain, or yellowing skin promptly.

• Aspirin and other blood thinners can increase bleeding risk.
• Topiramate can raise the risk of high ammonia levels and confusion when used with divalproex.
• Other medicines that cause drowsiness, including alcohol, opioids, and some sleep medicines, can increase sedation.
• Certain seizure medicines and antibiotics may change divalproex levels or how it works.
• Lamotrigine levels can be affected and may need close monitoring if used together.

Store Dicorate ER 750 mg Tablet at room temperature in the original strip/box, away from moisture and excess heat.