Pramipex ER 1.5 mg Tablet

Pramipex ER 1.5 mg Tablet is a prescription anti-Parkinsonian medicine that contains 1.5 mg of pramipexole in each extended-release tablet. It belongs to the dopamine agonist class, which helps improve movement symptoms in Parkinson’s disease by acting on dopamine receptors in the brain. This product is used when a clinician decides an extended-release tablet at this strength is appropriate for ongoing symptom control. It should be taken exactly as prescribed and is not a cure for Parkinson’s disease.

How it works: Pramipexole works by stimulating dopamine receptors in the brain, helping to replace some of the dopamine signaling that is reduced in Parkinson’s disease. As an extended-release tablet, Pramipex ER 1.5 mg Tablet is formulated to release medicine slowly so levels stay steadier through the day.

Pramipex ER 1.5 mg Tablet is a higher-strength extended-release tablet, so it is generally suited for people whose doctor has already assessed their response to pramipexole and determined that this dose is appropriate. Compared with lower strengths, the 1.5 mg tablet delivers a larger amount of medicine per tablet and is typically used as part of a carefully adjusted regimen rather than as a starting dose for most patients. Because it is extended-release, the dose is designed to release gradually over time rather than acting like an immediate-release tablet.

• Parkinson’s disease
• Improve slowness of movement
• Help reduce stiffness
• Help with tremor
• Support symptom control as prescribed by a doctor

• Swallow the Pramipex ER 1.5 mg Tablet whole with water; do not crush, chew, or split it.
• Take it at the same time each day to keep a regular schedule.
• You may take it with or without food, but taking it with food may help lessen nausea.
• Do not switch this extended-release tablet with an immediate-release pramipexole product unless your doctor tells you to.
• If you miss a dose, follow your prescriber’s instructions; do not double up to make up for a missed tablet.
• Do not stop taking it suddenly without medical advice, because Parkinson’s symptoms may worsen.

Each Pramipex ER 1.5 mg Tablet provides 1.5 mg of pramipexole in one extended-release tablet. It may be taken once daily for many patients, but the exact schedule and whether this strength is used alone or as part of a stepwise titration plan depend on the doctor’s judgment. The maximum daily dose is individualized and should not be changed without medical advice, especially with this higher-strength tablet.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Pramipexole may include:

• Nausea
• Dizziness
• Sleepiness or unusual drowsiness
• Constipation
• Dry mouth
• Swelling in the legs or feet
• More noticeable sleepiness at higher strengths

• This is a higher-strength pramipexole tablet, so dose changes should be made only by a doctor.
• It can cause sleepiness or sudden sleep attacks, so avoid driving or operating machinery until you know how it affects you.
• Alcohol may worsen dizziness or sleepiness.
• Use caution if you have kidney problems, because pramipexole is removed through the kidneys and dosing may need adjustment.
• Tell your doctor if you have hallucinations, low blood pressure, or a history of impulse-control problems.
• Report new swelling, shortness of breath, or chest discomfort promptly.
• Do not crush or chew the tablet, because that can affect the extended-release design.

• Other medicines that cause drowsiness, including sedatives, opioids, and some sleep medicines
• Alcohol
• Antipsychotic medicines that block dopamine effects
• Certain blood pressure medicines that may increase dizziness or low blood pressure
• Metoclopramide and similar dopamine-blocking drugs

Store Pramipex ER 1.5 mg Tablet at room temperature in its original strip/box, away from moisture and excess heat.