Requip XL 8 mg Tablet

Requip XL 8 mg Tablet contains 8 mg of ropinirole in each extended-release tablet. It belongs to the dopamine agonist class and is used to treat the symptoms of Parkinson’s disease. This strength is a higher-dose option for patients whose doctor has already determined they need more than the lower Requip XL 2 mg Tablet or Requip XL 4 mg Tablet strengths. Requip XL 8 mg Tablet is designed for once-daily use as part of a doctor-guided Parkinson’s treatment plan.

How it works: Ropinirole works by stimulating dopamine receptors in the brain, helping replace some of the dopamine activity that is reduced in Parkinson’s disease. Because Requip XL 8 mg Tablet is an extended-release tablet, it releases ropinirole slowly over time to provide steadier symptom control through the day.

Requip XL 8 mg Tablet is a higher-strength extended-release tablet, so it is usually chosen only after a lower strength has been tolerated or when a prescriber needs a larger total daily dose. Compared with Requip XL 2 mg Tablet and Requip XL 4 mg Tablet, the 8 mg tablet can reduce the number of tablets needed, but it is not the usual starting strength and may be more likely to cause dose-related side effects if increased too quickly.

• Parkinson’s disease symptom control
• Muscle stiffness and rigidity
• Tremor related to Parkinson’s disease
• Slowness of movement
• Extended-release once-daily ropinirole therapy

• Swallow Requip XL 8 mg Tablet whole with water; do not crush, chew, or split it.
• Take it once daily exactly as prescribed by your doctor, usually at the same time each day.
• You may take it with or without food, but taking it with food can help reduce nausea.
• Do not switch to the 8 mg tablet from a lower strength unless your prescriber tells you to do so.
• If you miss a dose, follow your doctor’s instructions; do not double up to make up for a missed tablet.
• If you notice tablet shell remnants in your stool, that can happen with some extended-release tablets and does not always mean the medicine was not absorbed.

Each Requip XL 8 mg Tablet provides 8 mg of ropinirole in one extended-release dose. It is typically taken once daily, but the exact schedule and the maximum daily dose are determined by the prescribing doctor based on response and tolerability. This is a higher-strength tablet, so it should be used only when a clinician has decided that this dose is appropriate for you.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Ropinirole may include:

• Nausea
• Dizziness
• Sleepiness or drowsiness
• Headache
• Constipation
• Fatigue
• Swelling in the legs or feet

• Requip XL 8 mg Tablet is a higher-strength dose and should not be used as a starting dose unless your doctor specifically prescribes it.
• It can cause marked drowsiness or sudden sleep episodes, so avoid driving or operating machinery until you know how it affects you.
• Alcohol can worsen dizziness and sleepiness.
• Tell your doctor if you have low blood pressure, heart disease, liver disease, or a history of fainting.
• Use caution when standing up quickly because this medicine can cause orthostatic hypotension.
• Report new hallucinations, confusion, or changes in behavior promptly, especially at higher doses.
• Tell your prescriber if you develop swelling, shortness of breath, or unusual sleepiness.

• Levodopa and other Parkinson’s medicines may need dose adjustments when used with ropinirole.
• CNS depressants such as alcohol, benzodiazepines, opioids, or sleep medicines can increase drowsiness.
• Blood pressure medicines may increase the risk of lightheadedness or fainting.
• Estrogens and certain hormone therapies can affect ropinirole levels.
• Ciprofloxacin and other CYP1A2 inhibitors can increase ropinirole exposure.

Store Requip XL 8 mg Tablet at room temperature in the original strip/box, away from moisture and heat, and keep it out of reach of children.