Esiflo Hfa 125 Transhaler

Esiflo Hfa 125 Transhaler is a prescription combination inhaler that contains salmeterol and fluticasone propionate in the labeled 125 strength per inhaler. It belongs to the long-acting beta agonist (LABA) plus inhaled corticosteroid class and is used for maintenance treatment of asthma. Esiflo Hfa 125 Transhaler helps reduce airway inflammation and keep airways open so breathing is easier over time. It is not a rescue medicine for sudden asthma symptoms.

How it works: Salmeterol relaxes the muscles around the airways for long-lasting bronchodilation, while fluticasone propionate lowers swelling and mucus in the lungs. In the Esiflo Hfa 125 Transhaler, these two medicines work together to help prevent asthma symptoms when used regularly as prescribed.

Esiflo Hfa 125 Transhaler is the lower-strength option among the Esiflo products listed here, compared with Esiflo 250 Transhaler and Esiflo 500 Transcaps. A doctor may choose this strength for people whose asthma is controlled with a lower maintenance dose or who need less corticosteroid exposure while still using a combination inhaler.

• Maintenance treatment of asthma
• Prevention of wheezing
• Reduction of shortness of breath from asthma
• Help with nighttime asthma symptoms
• Long-term control, not quick relief

• Use Esiflo Hfa 125 Transhaler exactly as prescribed by your doctor; it is not meant for sudden breathing trouble.
• Take it by inhalation only, not by mouth, and do not swallow the contents.
• Use it at the same times each day if your doctor has prescribed a regular schedule.
• Follow the inhaler-specific instructions for priming, shaking, inhaling, and holding your breath after each dose.
• Rinse your mouth with water after use and spit it out to lower the risk of oral thrush.
• Do not use extra doses for an asthma attack; keep a fast-acting rescue inhaler available if prescribed.

Each Esiflo Hfa 125 Transhaler provides the labeled 125 strength of salmeterol plus fluticasone propionate per inhaler, making it a lower maintenance strength than Esiflo 250 Transhaler or Esiflo 500 Transcaps. The exact number of inhalations and how often to use it depends on the prescription your doctor writes; do not exceed the prescribed daily amount. For asthma, the doctor decides whether this strength is appropriate and whether you need a higher or lower maintenance dose.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Salmeterol + Fluticasone Propionate may include:

• Throat irritation
• Hoarseness
• Cough after inhalation
• Headache
• Oral thrush in the mouth or throat
• Upper respiratory infection symptoms
• Tremor or feeling shaky

• Not for sudden asthma attacks; use a rescue inhaler for quick relief if prescribed.
• Because this is a combination inhaler, it is generally used as a maintenance medicine under a doctor’s supervision.
• Tell your doctor if you have heart disease, high blood pressure, irregular heartbeat, thyroid disease, diabetes, or seizures.
• Long-term or higher-dose use can raise the risk of steroid-related effects such as oral thrush and adrenal suppression.
• Use caution if you have active or recurrent infections, including tuberculosis, because inhaled steroids can affect immunity.
• Do not stop suddenly without medical advice, especially if your asthma has been controlled on this strength.
• Avoid sharing your inhaler with anyone else.

• Strong CYP3A4 inhibitors such as ritonavir or ketoconazole can increase fluticasone exposure.
• Other long-acting beta agonists should not be used together unless your prescriber specifically directs it.
• Beta-blockers may reduce the bronchodilator effect and can worsen breathing.
• Diuretics or other medicines that lower potassium may increase the risk of low potassium with salmeterol.
• Monoamine oxidase inhibitors and tricyclic antidepressants can increase cardiovascular side effects.

Store Esiflo Hfa 125 Transhaler at room temperature and keep it dry, away from heat, flame, and moisture, with the cap on when not in use.