Seretide 50 mcg/250 mcg Accuhaler

Seretide 50 mcg/250 mcg Accuhaler is a combination asthma medicine containing salmeterol 50 mcg and fluticasone propionate 250 mcg in each dose. It belongs to the long-acting beta2-agonist plus inhaled corticosteroid class and is used for regular control of asthma symptoms, not for quick relief of sudden breathing problems. Because this is a 50 mcg/250 mcg Accuhaler, it delivers a medium-strength steroid dose with a bronchodilator to help open the airways and reduce inflammation. It is supplied as a strip/box of 10 doses from GSK, India.

How it works: Salmeterol relaxes the muscles around the airways so air can move more easily in and out of the lungs. Fluticasone propionate reduces swelling and irritation inside the airways, and in the Seretide 50 mcg/250 mcg Accuhaler tablet form it is used as a regular controller rather than a rescue medicine.

Seretide 50 mcg/250 mcg Accuhaler is the lowest strength in the range you listed, and it is often chosen when a doctor wants regular asthma control without jumping straight to the higher 50 mcg/500 mcg Accuhaler. Compared with the 250 mcg Accuhaler sibling, this product combines a lower fluticasone dose with salmeterol in the same inhaled dose, which may be better suited to patients who need maintenance therapy but do not require the highest available steroid strength. Because it is a prescription-only asthma controller, the right strength depends on symptom history, lung function, and prior inhaler use.

• Maintenance treatment of asthma
• Prevention of daytime and nighttime asthma symptoms
• Reduction of wheeze and shortness of breath
• Help in lowering flare-up risk when used regularly
• Long-term control therapy prescribed by a doctor

• Take exactly as prescribed; this is not a medicine for sudden asthma attacks.
• Use the dose by inhalation from the Accuhaler device, not by swallowing the tablet content.
• Open and load the device only when you are ready to take a dose.
• Breathe out fully away from the device, then inhale the dose steadily and deeply through the mouthpiece.
• Rinse your mouth with water and spit it out after each use to help reduce thrush.
• Do not use more often than prescribed or stop suddenly without medical advice.

Each dose of Seretide 50 mcg/250 mcg Accuhaler provides salmeterol 50 mcg plus fluticasone propionate 250 mcg. The doctor decides how often you should use it, but it is commonly taken twice daily for asthma control; it should not be used as a reliever for acute symptoms. The maximum daily amount depends on the prescriber’s plan, and you should not exceed the number of inhalations your doctor has set for this 50 mcg/250 mcg strength.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Salmeterol + Fluticasone Propionate may include:

• Hoarseness or voice changes
• Sore throat
• Oral thrush (more likely if you do not rinse your mouth)
• Headache
• Tremor or shakiness
• Fast heartbeat or palpitations
• Cough or throat irritation

• Do not use Seretide 50 mcg/250 mcg Accuhaler for a sudden asthma attack; keep a fast-acting rescue inhaler available if prescribed.
• This is a medium-strength controller inhaler, so the dose should only be used if a clinician has assessed that this strength is appropriate.
• Tell your doctor if you have heart disease, high blood pressure, irregular heartbeat, diabetes, thyroid disease, seizures, or low potassium.
• Use caution if you are sensitive to beta-agonists because salmeterol can cause tremor, palpitations, or nervousness.
• Rinse and spit after each dose to lower the risk of oral thrush and throat irritation.
• Do not stop the inhaled steroid suddenly unless your doctor tells you to.
• If you notice more wheezing after use, seek medical help right away.

• Other LABA or asthma medicines that contain salmeterol or similar bronchodilators
• Strong CYP3A4 inhibitors such as ritonavir, cobicistat, ketoconazole, or itraconazole
• Beta-blockers such as propranolol, which may reduce bronchodilator effect
• Diuretics or medicines that can lower potassium
• Some antidepressants or heart medicines that can affect heart rhythm

Store the Seretide 50 mcg/250 mcg Accuhaler in a dry place at room temperature, away from moisture and heat, and keep it closed until use.