Istavel 100 mg Tablet

Istavel 100 mg Tablet contains 100 mg of sitagliptin in each tablet. It is an oral diabetes medicine in the DPP-4 inhibitor class, used along with diet and exercise to help improve blood sugar control in adults with type 2 diabetes. It is not used to treat type 1 diabetes or diabetic ketoacidosis. Istavel 100 mg Tablet is a higher-strength sitagliptin tablet that a clinician may choose when the 100 mg dose is appropriate for the patient.

How it works: Sitagliptin helps the body release more insulin after meals and lowers the amount of sugar made by the liver when blood sugar is high. As a tablet, Istavel 100 mg Tablet is swallowed and absorbed to support better day-to-day blood glucose control.

Compared with Istavel 50 mg Tablet, Istavel 100 mg Tablet provides a full 100 mg sitagliptin dose in one tablet, so it is intended for patients whose prescriber has decided that this higher strength fits their treatment plan. It does not usually work faster or feel stronger right away; rather, the difference is the amount of medicine delivered per tablet and how it matches the prescribed daily dose.

• Type 2 diabetes mellitus
• Blood sugar control with diet and exercise
• Add-on therapy with other diabetes medicines
• Reduction of high post-meal blood sugar
• Long-term glycemic management

• Swallow Istavel 100 mg Tablet whole with water; do not crush, chew, or split unless your prescriber says otherwise.
• Take it at the same time each day to help you remember your dose.
• It can be taken with or without food.
• Use it exactly as prescribed; this 100 mg tablet is a full-strength dose and should not be doubled on your own.
• If you also use insulin or a sulfonylurea, follow your clinician’s instructions closely to reduce the risk of low blood sugar.

Each Istavel 100 mg Tablet contains 100 mg of sitagliptin. The usual adult dose may be once daily, but the exact schedule, whether once daily or adjusted for kidney function, must be decided by your doctor. Do not take more than 100 mg in one day unless a healthcare professional specifically tells you to do so.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sitagliptin may include:

• Upper respiratory tract symptoms such as a runny or stuffy nose
• Headache
• Sore throat
• Diarrhea
• Nausea
• Back pain
• Mild swelling or fluid retention when used with certain other diabetes medicines

• Tell your prescriber if you have kidney disease, because the dose may need to be changed for this 100 mg tablet.
• Use caution if you take insulin or a sulfonylurea, since blood sugar can drop too low when medicines are combined.
• Do not use this medicine to treat type 1 diabetes or diabetic ketoacidosis.
• Report any history of pancreatitis to your clinician before starting treatment.
• Tell your doctor about heart failure or swelling, especially if you take other diabetes medicines that can cause fluid retention.
• If you drink alcohol, ask your clinician how much is safe, because alcohol can affect blood sugar control.
• Check your blood sugar as directed and be alert for symptoms of low or high blood sugar, especially when starting or changing therapy.

• Insulin
• Sulfonylureas such as glipizide or glyburide
• Other medicines that can lower blood sugar
• Digoxin
• Strong prescription medicines that affect kidney function or drug handling

Store Istavel 100 mg Tablet in its original strip or box at room temperature, away from moisture and excessive heat.