Utreva Vaginal gel

Utreva Vaginal gel is a progesterone vaginal gel made by Intas Pharmaceuticals Ltd. Each tube contains progesterone as labelled, and it belongs to the progestogen hormone class. It is used as part of infertility treatment, especially when progesterone support is needed for the lining of the uterus and early pregnancy support in assisted reproduction. Because it is a vaginal gel, Utreva Vaginal gel delivers progesterone locally through the vaginal route rather than as a pill.

How it works: Progesterone helps prepare the uterine lining so an embryo can attach and grow more easily. As a vaginal gel, Utreva Vaginal gel places progesterone close to the reproductive tissues, which can help maintain a supportive environment for fertility treatment.

Utreva Vaginal gel is a specific progesterone gel strength in tube form, so it is meant for people whose doctor has decided that vaginal progesterone is the right option. Compared with lower-strength products, this as-labelled gel is chosen when the prescribed progesterone exposure needs to be delivered in a single tube dose, with vaginal use helping the medicine act directly at the treatment site. A doctor may choose this form when they want a non-oral option that may be easier to tolerate and simpler to use than repeated tablets.

• Progesterone support in infertility treatment
• Luteal phase support
• Support during assisted reproductive procedures
• Help maintain the uterine lining
• Use only when prescribed by a doctor

• Use Utreva Vaginal gel exactly as your doctor prescribed; do not change the schedule on your own.
• Apply the tube vaginally, usually with the applicator if provided, and follow the package directions for the full tube dose.
• Use it at the same time each day if your prescriber has set a daily schedule.
• Wash your hands before and after use to reduce irritation and contamination.
• If you are instructed to use it at bedtime, lie down afterward when possible to help the gel stay in place.
• Do not take it by mouth unless a clinician specifically tells you to do so.

Each tube of Utreva Vaginal gel contains progesterone as labelled, and the full tube is generally used as one prescribed dose. How often it is used can vary by fertility protocol, commonly once daily or as directed by the prescriber, and the maximum daily amount depends on the treatment plan rather than patient choice. Your doctor decides the exact dose, timing, and duration for this specific Utreva Vaginal gel product.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Progesterone may include:

• Vaginal discharge or leakage of the gel
• Mild vaginal irritation or burning
• Headache
• Breast tenderness
• Bloating
• Drowsiness or tiredness

• Use only under the supervision of a fertility or women’s health clinician.
• Tell your doctor if you have a history of breast cancer, blood clots, stroke, liver disease, or unexplained vaginal bleeding.
• This vaginal gel may cause drowsiness in some people, so use caution with driving or tasks that need alertness until you know how you react.
• Avoid using other vaginal products unless your doctor says they are okay, because they may affect absorption or cause irritation.
• Tell your prescriber if you are pregnant, breastfeeding, or think you may be pregnant, because progesterone use must be individualized.
• Do not use more than prescribed; higher exposure does not mean better fertility results and may increase side effects.
• If you develop severe pain, clot symptoms, or heavy bleeding, seek urgent medical care.

• Other hormone medicines, including estrogen or other progestins
• Blood thinners such as warfarin
• Medicines that may affect hormone levels or metabolism, including some seizure medicines and rifampin
• Ritonavir-containing HIV medicines and other strong enzyme modifiers
• Other vaginal medicines or products that may irritate the vaginal area

Store Utreva Vaginal gel at room temperature in the original pack, away from excess heat, moisture, and direct light, and keep it out of reach of children.