Zyrik 300 mg Tablet

Zyrik 300 mg Tablet is a prescription medicine containing 300 mg of allopurinol in each tablet. Allopurinol is a xanthine oxidase inhibitor used to lower uric acid levels in the body. Zyrik 300 mg Tablet is used to help prevent gout attacks, treat high uric acid levels, and reduce the risk of uric acid kidney stones in people who need long-term urate control.

How it works: Allopurinol works by blocking an enzyme that helps your body make uric acid. In this tablet form, Zyrik 300 mg Tablet is taken by mouth so the medicine can lower uric acid levels over time and help prevent crystal buildup in joints and kidneys.

Zyrik 300 mg Tablet is a higher-strength tablet and is not usually the first dose started for many patients. Doctors may choose Zyrik 300 mg Tablet after checking kidney function, uric acid levels, and how well lower strengths such as Zyrik 100 mg Tablet are working. It is suited for people who need a larger maintenance dose rather than a small starting dose.

• Prevention of gout attacks
• Treatment of hyperuricemia
• Prevention of uric acid kidney stones
• Uric acid control in certain cancer treatments
• Long-term urate-lowering therapy

• Swallow Zyrik 300 mg Tablet whole with a glass of water.
• Take it after food if you get stomach upset, unless your doctor tells you otherwise.
• Take it at the same time each day to help you remember.
• Drink plenty of fluids unless your doctor has told you to limit fluids.
• Do not crush or chew the tablet unless your pharmacist says it is safe to do so.
• If your doctor changes your dose, follow the new schedule exactly rather than adjusting it yourself.

Each Zyrik 300 mg Tablet provides 300 mg of allopurinol per tablet. Your doctor decides how many tablets you should take and how often, based on your condition, kidney function, and uric acid levels; some patients take it once daily, while others may need a different schedule. Do not take more tablets per day than prescribed, because the maximum daily dose must be individualized by your prescriber.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Allopurinol may include:

• Rash
• Nausea
• Diarrhea
• Upset stomach
• Sleepiness or dizziness
• More frequent side effects if the dose is increased too quickly

• Zyrik 300 mg Tablet is a higher-strength allopurinol tablet and should be used only as prescribed after a doctor reviews your needs.
• Tell your doctor if you have kidney disease, liver disease, or a history of gout flares when starting urate-lowering therapy.
• Allopurinol can trigger a gout flare when treatment begins, so your doctor may recommend another medicine to help prevent flares.
• Stay well hydrated unless told otherwise, because fluid intake helps lower the risk of kidney stones.
• Use caution with alcohol, since it can raise uric acid and worsen gout control.
• Do not drive or use machinery if Zyrik 300 mg Tablet makes you dizzy or sleepy.
• Report any rash right away, especially in the first weeks of treatment, because serious skin reactions can happen.

• Azathioprine
• Mercaptopurine
• Warfarin
• Diuretics such as thiazides
• Ampicillin or amoxicillin

Store Zyrik 300 mg Tablet in its original strip/box at room temperature, away from moisture and heat, and keep it out of reach of children.