Esiflo 250 Transhaler

Esiflo 250 Transhaler is a prescription inhalation medicine that contains salmeterol and fluticasone propionate in the 250 strength per inhaler as labeled. It combines a long-acting bronchodilator with an inhaled corticosteroid to help control asthma symptoms over time. Esiflo 250 Transhaler is used for ongoing maintenance treatment, not for quick relief of sudden breathing problems. This product is manufactured by Lupin, India, and is supplied as a strip/box of 10 inhalers.

How it works: Salmeterol relaxes the muscles around the airways so they stay open longer and breathing feels easier. Fluticasone propionate reduces airway inflammation and swelling, helping prevent wheezing, cough, and asthma flare-ups with regular use of this inhaled form.

Esiflo 250 Transhaler is a higher-strength option compared with lower-strength Esiflo Hfa 125 Transhaler, so it is generally chosen when a doctor wants stronger maintenance control rather than a lower starting dose. It may also be used in people whose asthma has not been adequately controlled on a lower strength, while Esiflo 500 Transcaps represents an even higher-step option. The exact strength and device are selected by a clinician based on symptom control, prior inhaler response, and asthma severity.

• Maintenance treatment of asthma
• Prevention of wheezing and shortness of breath
• Long-term control of airway inflammation
• Reduction of day-to-day asthma symptoms
• Help in preventing asthma flare-ups

• Use Esiflo 250 Transhaler exactly as prescribed; it is not a rescue medicine for sudden asthma attacks.
• If you were shown how to use the inhaler, follow those instructions carefully and use it the same way each time.
• Breathe in the dose through the inhaler as directed by your doctor, then hold your breath for a few seconds if instructed.
• Rinse your mouth with water and spit after use to lower the risk of oral thrush and hoarseness.
• Do not increase the number of inhalations or use it more often just because symptoms are bothering you.
• If you need quick relief medicine more often than usual, contact your doctor rather than taking extra Esiflo 250 Transhaler.

Esiflo 250 Transhaler delivers the 250-strength salmeterol plus fluticasone propionate dose as labeled in each inhaler, which is a stronger maintenance option than Esiflo Hfa 125 Transhaler. The exact schedule is set by the doctor and may be once or twice daily depending on asthma control; do not use more than the prescribed number of inhalations per day. Your clinician decides whether this higher strength is appropriate for you, especially if lower-strength treatment has not been enough.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Salmeterol + Fluticasone Propionate may include:

• Hoarseness or voice changes
• Sore throat
• Mouth or throat irritation
• Headache
• Cough after inhalation
• Oral thrush, especially if the mouth is not rinsed after use
• Tremor or a feeling of jitteriness

• This is a controller inhaler and should not be used for immediate relief of sudden asthma symptoms.
• Because Esiflo 250 Transhaler is a higher-strength inhaled steroid/LABA combination, only use it if a doctor has assessed that this strength is appropriate.
• Tell your doctor if you have heart disease, high blood pressure, irregular heartbeat, thyroid disease, diabetes, glaucoma, cataracts, or seizures.
• Rinse and spit after each use to reduce the risk of thrush, which can be more of a concern with higher inhaled steroid exposure.
• Use caution if you drink alcohol, especially if it tends to trigger your asthma or worsen side effects like dizziness.
• Tell your doctor if you are taking other steroids, since long-term higher-dose inhaled steroid use can add to steroid effects.
• Do not stop the inhaler suddenly without medical advice, especially if you have been using it regularly.

• Other long-acting beta agonists or asthma inhalers containing salmeterol or similar medicines
• Strong CYP3A4 inhibitors such as ketoconazole, itraconazole, ritonavir, or cobicistat
• Beta-blockers, which can reduce the bronchodilator effect and may worsen asthma
• Other corticosteroids, including oral or injectable steroids, which can increase total steroid exposure

Store Esiflo 250 Transhaler in a cool, dry place away from moisture, heat, and direct sunlight, and keep it in the original package until use.