Empaone-M ER 25/1000 Tablet

Empaone-M ER 25/1000 Tablet is a prescription diabetes medicine that combines empagliflozin 25 mg and metformin 1000 mg in one extended-release tablet. It belongs to the SGLT2 inhibitor plus biguanide class and is used along with diet and exercise to help improve blood sugar control in adults with type 2 diabetes. This strength is a higher-dose option, so it is generally chosen only after a doctor decides that lower-strength tablets are not enough. Empaone-M ER 25/1000 Tablet is not used for type 1 diabetes or for diabetic ketoacidosis.

How it works: Empagliflozin helps the kidneys remove extra glucose into the urine, which lowers blood sugar. Metformin helps the body use insulin better and reduces the amount of glucose made by the liver, and the tablet is made to release metformin over time.

Empaone-M ER 25/1000 Tablet contains the higher labeled amounts of both ingredients compared with Empaone-M IR 12.5/500 Tablet, so it is not a starting-strength tablet for most people. Because it is an extended-release form, it is designed for once-daily use and may be chosen when a doctor wants stronger blood sugar lowering with a smoother, longer-lasting effect than immediate-release tablets. The exact fit depends on kidney function, previous diabetes control, and how well the lower-strength Empaone-M Tablet ER is working.

• Type 2 diabetes mellitus
• Improving blood sugar control
• Adjunct to diet and exercise
• Combination therapy when one medicine is not enough
• May help lower the risk of diabetes-related complications when prescribed appropriately

• Swallow Empaone-M ER 25/1000 Tablet whole with water; do not crush, split, or chew it.
• Take it once daily exactly as prescribed, preferably with the same meal each day to reduce stomach upset.
• Do not take extra tablets if you miss a dose; follow your prescriber’s instructions for missed doses.
• Because this is an extended-release tablet, do not change it to a lower-strength tablet or immediate-release form unless your doctor tells you to.
• Drink enough fluids, especially in hot weather or if you have vomiting or diarrhea, because empagliflozin can increase urination.
• If you are having an imaging test or surgery, tell your doctor that you take empagliflozin and metformin before the procedure.

Each Empaone-M ER 25/1000 Tablet provides empagliflozin 25 mg plus metformin 1000 mg in one tablet. This higher-strength ER product is usually taken once daily, and the maximum daily amount is generally one tablet per day unless a doctor specifically changes the regimen. Your prescriber decides the dose based on your blood sugar readings, kidney function, and how you respond to treatment.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Empagliflozin + Metformin may include:

• Diarrhea
• Nausea
• Stomach upset
• Gas or bloating
• Increased urination
• Genital yeast infection
• Urinary tract infection; these may be more noticeable because of the 25 mg empagliflozin strength

• This is a higher-strength tablet, so it should be used only when a doctor has assessed that the dose is appropriate.
• Do not use for type 1 diabetes or if you have diabetic ketoacidosis.
• Metformin-containing products may not be appropriate if you have significantly reduced kidney function.
• Avoid heavy alcohol use, which can raise the risk of lactic acidosis with metformin.
• Be careful when standing up quickly, since empagliflozin can cause fluid loss and low blood pressure.
• Tell your doctor before surgery, fasting, or major illness because you may need temporary dose changes.
• Use caution when driving or operating machinery until you know how this tablet affects your blood sugar and dizziness risk.

• Insulin or sulfonylureas, which can increase the risk of low blood sugar
• Diuretics or water pills, which can worsen dehydration and low blood pressure
• Alcohol, which increases the risk of metformin-related lactic acidosis
• Contrast dye used for some scans, which may require temporary stopping of metformin-containing medicines
• Rifampin or other medicines that affect drug handling in the body, which may change empagliflozin levels

Store Empaone-M ER 25/1000 Tablet at room temperature in the original strip/box, away from moisture and excessive heat.