Gibtulio Met 12.5 mg/1000 mg Tablet

Gibtulio Met 12.5 mg/1000 mg Tablet is a prescription diabetes medicine that combines empagliflozin 12.5 mg and metformin 1000 mg in each tablet. It belongs to two antidiabetic classes: an SGLT2 inhibitor and a biguanide. Doctors use Gibtulio Met 12.5 mg/1000 mg Tablet to help improve blood sugar control in adults with type 2 diabetes, along with diet and exercise. This specific tablet strength is meant for people whose treatment plan needs both ingredients at this higher metformin dose in one tablet.

How it works: Empagliflozin helps your kidneys remove extra sugar through urine, while metformin lowers the amount of sugar your liver makes and helps your body use insulin better. As a tablet, Gibtulio Met 12.5 mg/1000 mg Tablet delivers both medicines together in one dose to support steadier blood sugar control.

Gibtulio Met 12.5 mg/1000 mg Tablet is the higher-strength option compared with Gibtulio Met 12.5 mg/500 mg Tablet because it contains double the metformin in each tablet while the empagliflozin dose stays the same. A clinician may choose this strength for a person who has already been assessed and needs a stronger metformin component, rather than starting with the lower-strength tablet. Because metformin 1000 mg is a higher dose, some people may notice gastrointestinal side effects more readily when this strength is started or increased.

• Type 2 diabetes blood sugar control
• Adjunct to diet and exercise
• Combination therapy when one medicine is not enough
• May help reduce blood sugar after meals and between meals

• Swallow the tablet whole with water; do not crush, split, or chew it unless your prescriber specifically tells you to.
• Take Gibtulio Met 12.5 mg/1000 mg Tablet with food if it upsets your stomach, especially because of the 1000 mg metformin strength.
• Take it at the same time each day to help you remember and keep blood sugar control steady.
• Stay well hydrated, especially in hot weather or if you are active, because empagliflozin can increase urination.
• If you miss a dose, take it when you remember unless it is close to the next dose; do not double up.
• Follow the exact schedule your doctor gives you, since this strength is not for self-adjusting.

Each tablet of Gibtulio Met 12.5 mg/1000 mg Tablet provides empagliflozin 12.5 mg plus metformin 1000 mg. Depending on your prescription, it may be taken once or twice daily, but the exact schedule is decided by your doctor based on your blood sugar, kidney function, and how you respond to treatment. Do not take more than the maximum total daily amount prescribed by your clinician.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Empagliflozin + Metformin may include:

• Diarrhea, which may be more noticeable with the 1000 mg metformin strength
• Nausea or vomiting
• Stomach pain or bloating
• Loss of appetite
• Increased urination
• Genital yeast infection
• Thirst or mild dehydration

• This is a higher-strength tablet, so it should be used only when a doctor has decided the 1000 mg metformin dose is appropriate.
• Do not use if you have severe kidney disease unless your prescriber specifically says it is safe.
• Alcohol can raise the risk of lactic acidosis and should be limited or avoided unless your clinician approves.
• Tell your doctor if you have heart disease, heart failure, low blood pressure, or a history of dehydration.
• Stop and seek care if you develop symptoms of diabetic ketoacidosis, even if your blood sugar is not very high.
• Use caution when driving or operating machinery until you know how this tablet affects you, especially if it causes dizziness or low blood sugar with other diabetes medicines.
• Tell your doctor about surgery, fasting, vomiting, or diarrhea, because this tablet may need to be held temporarily.

• Insulin or sulfonylureas, which can increase the risk of low blood sugar
• Diuretics or water pills, which can worsen dehydration and low blood pressure
• Iodinated contrast dye used for imaging studies, which may require temporary stopping of metformin-containing products
• Alcohol, which can increase the risk of lactic acidosis
• Certain HIV or seizure medicines may affect blood sugar control or drug handling

Store Gibtulio Met 12.5 mg/1000 mg Tablet at room temperature in its original pack, away from moisture and excessive heat.