Gibtulio Met 12.5 mg/500 mg Tablet

Gibtulio Met 12.5 mg/500 mg Tablet is a prescription diabetes medicine that combines empagliflozin 12.5 mg and metformin 500 mg in each tablet. It belongs to the SGLT2 inhibitor plus biguanide class and is used to help improve blood sugar control in adults with type 2 diabetes, along with diet and exercise. This box contains 10 strips/packs of tablets from Lupin, India. It is not for type 1 diabetes or for treating diabetic ketoacidosis.

How it works: Empagliflozin helps the kidneys pass extra glucose into the urine, which lowers blood sugar. Metformin helps the liver release less sugar and helps the body use insulin better, and in this tablet the two medicines work together for steadier glucose control.

Gibtulio Met 12.5 mg/500 mg Tablet is the lower of the two listed strengths, and it provides less metformin than Gibtulio Met 12.5 mg/1000 mg Tablet. A doctor may choose this strength for someone who needs the empagliflozin-metformin combination but may tolerate a smaller metformin dose better, especially if side effects like stomach upset are a concern. It is still a full prescription-strength tablet and should only be used when a clinician has decided this exact strength is appropriate.

• Type 2 diabetes blood sugar control
• Add-on therapy with diet and exercise
• Improving fasting and after-meal glucose levels
• Combination treatment when one medicine is not enough

• Swallow the tablet whole with water; do not chew, crush, or split it.
• Take it exactly as prescribed by your doctor, usually at the same time each day.
• It may be taken with food to help reduce stomach upset from metformin.
• Drink enough fluids unless your doctor has told you to restrict fluids.
• If you miss a dose, take it when remembered unless it is almost time for the next dose; do not double up.
• Follow your diabetes meal plan and monitor blood sugar as advised.

Each tablet of Gibtulio Met 12.5 mg/500 mg provides empagliflozin 12.5 mg plus metformin 500 mg. How often it is taken and the maximum daily dose depend on your doctor’s plan and on your response, kidney function, and other medicines; this strength is not meant to be adjusted on your own. Because it contains metformin 500 mg, some patients are started on or maintained with this lower-strength tablet before moving to higher strengths if needed.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Empagliflozin + Metformin may include:

• Diarrhea, especially early in treatment
• Nausea or vomiting
• Stomach pain or gas
• Loss of appetite
• Increased urination
• Mild dehydration or thirst
• Genital yeast infection

• This strength is prescription-only and should be used only for type 2 diabetes, not type 1 diabetes.
• Lower metformin exposure than the 12.5 mg/1000 mg tablet may make it a better fit for patients who need a smaller metformin dose.
• Tell your doctor if you have kidney disease, because metformin and empagliflozin may not be appropriate if kidney function is reduced.
• Avoid heavy alcohol use, which can increase the risk of lactic acidosis with metformin.
• Stay hydrated; empagliflozin can increase urination and may cause dehydration or low blood pressure.
• Use caution if you drive or operate machinery until you know how this tablet affects your blood sugar and energy.
• Seek medical advice before surgery, severe illness, fasting, or major changes in diet, because this medicine may need to be held temporarily.

• Insulin or sulfonylureas, which can increase the risk of low blood sugar
• Diuretics or water pills, which can increase dehydration risk
• Alcohol, which can raise the risk of lactic acidosis
• Iodinated contrast dye used for some imaging tests
• Cimetidine or other medicines that may affect kidney handling of metformin

Store Gibtulio Met 12.5 mg/500 mg Tablet at room temperature in the original strip/box, away from moisture and heat.