Jardiance Met 12.5 mg/500 mg Tablet

Jardiance Met 12.5 mg/500 mg Tablet is a prescription combination tablet that contains empagliflozin 12.5 mg and metformin 500 mg in each tablet. It belongs to the SGLT2 inhibitor and biguanide drug classes and is used along with diet and exercise to help improve blood sugar control in adults with type 2 diabetes. The Jardiance Met 12.5 mg/500 mg Tablet is not for type 1 diabetes or diabetic ketoacidosis. It is supplied as a tablet in a strip/box of 10 packs from Boehringer Ingelheim Pharmaceuticals.

How it works: In this tablet, empagliflozin helps the kidneys remove extra glucose in the urine, which lowers blood sugar. Metformin helps reduce the amount of sugar the liver releases and improves the body’s response to insulin.

Jardiance Met 12.5 mg/500 mg Tablet is a middle-strength combination, sitting between Jardiance Met 5 mg/500 mg Tablet and Jardiance Met 12.5 mg/1000 mg Tablet. Doctors may choose this strength when a patient needs the empagliflozin 12.5 mg component with a lower metformin amount than the 1000 mg tablet, or when the lower metformin load may be better tolerated. Because it is a higher-strength prescription tablet, it should only be used after a clinician has reviewed the person’s blood sugar needs, kidney function, and treatment goals.

• Helps improve blood sugar control in adults with type 2 diabetes
• Used together with diet and exercise
• May help lower A1C when prescribed appropriately
• Can be part of a diabetes treatment plan when one medicine is not enough

• Swallow the Jardiance Met 12.5 mg/500 mg Tablet whole with water; do not crush, chew, or split it unless your prescriber says otherwise.
• Take it exactly as prescribed, usually once daily, and try to take it at the same time each day.
• Taking the tablet with food may help reduce stomach upset from the metformin component.
• Drink enough fluids while using this tablet, especially in hot weather, during exercise, or if you have vomiting or diarrhea.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.
• Follow your doctor’s instructions for blood sugar checks, kidney labs, and diabetes diet while using this tablet.

Each tablet provides empagliflozin 12.5 mg plus metformin 500 mg. The Jardiance Met 12.5 mg/500 mg Tablet is usually taken once daily, but the exact schedule and whether this strength is appropriate depend on your doctor’s assessment. Do not exceed the amount your prescriber tells you to take; the maximum daily dose depends on your full treatment plan and kidney function.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Empagliflozin + Metformin may include:

• Diarrhea
• Nausea
• Stomach upset or abdominal pain
• Gas or bloating
• Increased urination
• Thirst or dry mouth
• Mild genital yeast infection, which may be more noticeable with empagliflozin

• Not for type 1 diabetes or diabetic ketoacidosis
• Do not use this strength without medical supervision, since it is a prescription combination tablet
• Metformin can increase the risk of lactic acidosis, especially with kidney disease, dehydration, heavy alcohol use, or severe infection
• Empagliflozin can cause genital yeast infections and urinary tract infections
• Use caution if you are older, have kidney problems, heart failure, or low blood pressure
• Avoid excessive alcohol, which can raise the risk of side effects and low blood sugar symptoms
• Be careful when driving or using machinery if you feel dizzy or weak

• Insulin or sulfonylureas, which can increase the risk of low blood sugar
• Diuretics, which may increase dehydration and dizziness
• Iodinated contrast dye used for some imaging tests, which may require the medicine to be held temporarily
• Alcohol, which can raise the risk of lactic acidosis and side effects from metformin
• Other diabetes medicines, which may need dose adjustment

Store the Jardiance Met 12.5 mg/500 mg Tablet at room temperature in the original strip/box, away from moisture and excess heat.