Glimet DS 5/500 mg Tablet

Glimet DS 5/500 mg Tablet is an oral diabetes medicine that combines glipizide 5 mg and metformin 500 mg in each tablet. It belongs to the sulfonylurea + biguanide class and is used, along with diet and exercise, to help lower blood sugar in adults with type 2 diabetes. This strength is a combination tablet, so it is meant for people whose doctor has decided they need both medicines together in one pill.

How it works: In Glimet DS 5/500 mg Tablet, glipizide helps the pancreas release more insulin when blood sugar is high, while metformin lowers the amount of sugar the liver makes and helps the body use insulin better. As a tablet swallowed by mouth, it works systemically to improve blood glucose control over time.

Glimet DS 5/500 mg Tablet is a higher-strength combination tablet because it contains both glipizide and metformin in a single dose. It may suit adults who need stronger blood sugar control than metformin alone can provide, or who are already stable on the two medicines and want a simpler regimen. Because it contains 500 mg metformin plus glipizide, a doctor chooses it based on prior response, blood sugar readings, and tolerability.

• Type 2 diabetes mellitus
• Blood sugar control with diet and exercise
• Combination therapy when one medicine is not enough
• May help lower fasting and after-meal glucose
• Used to reduce high blood sugar complications

• Swallow the Glimet DS 5/500 mg Tablet whole with water; do not crush, chew, or split unless your prescriber tells you otherwise.
• Take it with food to reduce stomach upset, especially because the metformin 500 mg part can cause nausea or diarrhea.
• Take it exactly at the time your doctor prescribes, often with meals and sometimes more than once daily depending on your glucose levels.
• Do not skip meals after taking glipizide-containing tablets, because taking it without food can raise the risk of low blood sugar.
• Follow your diabetes meal plan, exercise plan, and blood sugar monitoring schedule while using this tablet.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.

Each Glimet DS 5/500 mg Tablet provides glipizide 5 mg plus metformin 500 mg. The exact number of tablets per day depends on the doctor’s plan, blood sugar response, kidney function, and how well you tolerate the medicine; this is not a one-size-fits-all dose. The total daily dose is set by your prescriber, and higher amounts are only used when needed and when safe for this specific combination strength.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Glipizide + Metformin may include:

• Nausea
• Diarrhea
• Stomach pain or upset stomach
• Loss of appetite
• Headache
• Dizziness
• Low blood sugar, especially if meals are skipped or activity is increased

• Use caution if you have kidney disease, because metformin may not be appropriate or may need closer monitoring.
• Avoid heavy alcohol use, which can raise the risk of low blood sugar and metformin-related lactic acidosis.
• Be careful driving or operating machinery until you know how Glimet DS 5/500 mg Tablet affects you, especially if you get hypoglycemia.
• Tell your doctor if you have liver disease, heart failure, infection, fever, surgery, or major dehydration.
• Do not use it to treat type 1 diabetes or diabetic ketoacidosis.
• Older adults may be more sensitive to low blood sugar and kidney-related side effects.
• Inform your clinician if you are pregnant, planning pregnancy, or breastfeeding so diabetes treatment can be adjusted safely.

• Alcohol
• Insulin and other diabetes medicines such as sulfonylureas or meglitinides
• Some blood pressure medicines, including beta-blockers, which can mask low blood sugar symptoms
• Diuretics, corticosteroids, and certain asthma or cold medicines that can affect glucose levels
• Iodinated contrast dyes used for CT scans or other imaging tests

Store Glimet DS 5/500 mg Tablet in its original strip or box at room temperature, away from moisture, heat, and direct light.