Tripin OM 40 Tablet

Tripin OM 40 Tablet is a prescription combination medicine used to help lower high blood pressure. Each tablet contains olmesartan medoxomil, amlodipine, and hydrochlorothiazide at the labeled strength, combining an ARB, a calcium channel blocker, and a thiazide diuretic in one tablet. Tripin OM 40 Tablet is used for adults whose blood pressure is not controlled well enough with a single medicine or simpler combination treatment.

How it works: Olmesartan medoxomil helps relax blood vessels by blocking angiotensin II, a substance that tightens them. Amlodipine also relaxes blood vessels, and hydrochlorothiazide helps the body remove extra salt and water, so the tablet lowers blood pressure from three different angles.

Tripin OM 40 Tablet is a higher-strength tablet in this brand line and is typically chosen when a doctor needs a stronger blood-pressure-lowering effect than lower strengths can provide. Because it combines three medicines in one tablet, it is meant for patients who have already been assessed and need this exact fixed-dose strength rather than an initial, low-dose start.

• Treatment of high blood pressure (hypertension)
• May help reduce strain on the heart and blood vessels
• Used when a doctor needs triple therapy in one tablet
• May be prescribed when blood pressure remains above goal on other treatment

• Swallow Tripin OM 40 Tablet whole with water; do not crush or chew it unless your prescriber gives different instructions.
• Take it at the same time each day to help you remember your dose.
• It may be taken with or without food.
• Stand up slowly after taking it, especially when starting treatment, because it can cause dizziness or lightheadedness.
• Keep taking it even if you feel well, since high blood pressure often has no symptoms.
• Do not take extra tablets to make up for a missed dose unless your doctor or pharmacist tells you to do so.

Tripin OM 40 Tablet provides the labeled fixed dose of olmesartan medoxomil, amlodipine, and hydrochlorothiazide in each tablet. It is usually taken once daily, but the exact schedule depends on your blood pressure, kidney function, and other medicines; your doctor decides the right dose for you. Do not exceed the prescribed number of tablets per day, and this higher-strength tablet is not meant to be a casual starting dose.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Olmesartan Medoxomil + Amlodipine + Hydrochlorothiazide may include:

• Dizziness
• Lightheadedness
• Swelling in the ankles or feet
• Headache
• Tiredness
• Increased urination
• Nausea

• Tripin OM 40 Tablet can lower blood pressure too much, especially when you first start or if the dose is increased.
• Use caution if you are dehydrated, vomiting, having diarrhea, or sweating heavily, because hydrochlorothiazide can worsen fluid loss.
• Avoid alcohol or use it carefully, since it can increase dizziness and low blood pressure.
• Tell your doctor if you have kidney disease, liver disease, gout, diabetes, or heart problems before using this tablet.
• This medicine may not be appropriate during pregnancy, and it should be discussed urgently if pregnancy is possible or planned.
• Stand up slowly from sitting or lying positions to reduce the risk of falls.
• Driving or operating machinery may be risky until you know how Tripin OM 40 Tablet affects you.

• Other blood pressure medicines, especially other ARBs, ACE inhibitors, or aliskiren
• NSAIDs such as ibuprofen or naproxen, which can reduce the blood-pressure effect and stress the kidneys
• Lithium, which can reach dangerous levels
• Potassium supplements or potassium-sparing diuretics, which may raise potassium too much
• Certain heart medicines and strong CYP3A4 inhibitors that can increase amlodipine effects

Store Tripin OM 40 Tablet in the original strip or box at room temperature, away from moisture, heat, and direct light.