Tri-Olmetor 40 Tablet

Tri-Olmetor 40 Tablet is a prescription combination tablet for high blood pressure. Each tablet contains olmesartan medoxomil 40 mg, amlodipine 5 mg, and hydrochlorothiazide 12.5 mg. It combines an angiotensin II receptor blocker, a calcium channel blocker, and a thiazide diuretic to help lower blood pressure when one medicine alone is not enough. By reducing blood vessel tightening and helping the body remove extra salt and water, Tri-Olmetor 40 Tablet can help reduce the risk of blood pressure-related complications over time.

How it works: Tri-Olmetor 40 Tablet works in three ways: olmesartan relaxes blood vessels, amlodipine keeps calcium from tightening the vessel walls, and hydrochlorothiazide helps the kidneys remove extra salt and water. Taken as a tablet, these medicines work together to lower blood pressure more effectively than any one ingredient alone for many patients.

Tri-Olmetor 40 Tablet is the higher-strength sibling compared with Tri-Olmetor 20 Tablet, because it contains a larger olmesartan dose while keeping the same amlodipine and hydrochlorothiazide amounts. It may be chosen for adults whose blood pressure is not controlled well enough with lower-strength treatment or who need a doctor-assessed step up to a stronger tablet. Because it is a stronger olmesartan-containing tablet, it is generally meant for patients already evaluated for combination therapy rather than for starting treatment on a lower dose.

• Treatment of high blood pressure (hypertension)
• May be used when single-medicine treatment is not enough
• Helps lower the risk of blood pressure-related complications
• Used as part of long-term blood pressure management

• Swallow the Tri-Olmetor 40 Tablet whole with water; do not crush or chew it unless your doctor or pharmacist says otherwise.
• Take it at the same time each day to help you remember and to keep blood pressure control steady.
• It can be taken with or without food, but try to take it the same way each day.
• Because hydrochlorothiazide can increase urination, many people prefer taking it in the morning.
• Stand up slowly from sitting or lying down, especially when first starting Tri-Olmetor 40 Tablet, because it can cause dizziness or lightheadedness.
• Follow your doctor’s exact instructions; do not change the dose on your own.

This tablet provides olmesartan medoxomil 40 mg, amlodipine 5 mg, and hydrochlorothiazide 12.5 mg in each tablet. The usual schedule is once daily, but your doctor decides whether this strength is appropriate for you and whether any adjustment is needed. Do not take more than 1 tablet in 24 hours unless your prescriber specifically tells you to.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Olmesartan Medoxomil + Amlodipine + Hydrochlorothiazide may include:

• Dizziness or lightheadedness, especially after the first doses or when standing up
• Swelling of the ankles or feet
• Headache
• Fatigue or tiredness
• Increased urination
• Nausea
• Muscle cramps or weakness

• Tri-Olmetor 40 Tablet is a higher-strength combination tablet and should be used only if your doctor has assessed that you need this dose.
• It can cause dehydration or low blood pressure, so be careful in hot weather, during vomiting/diarrhea, or if you are not drinking enough fluids.
• Avoid taking potassium supplements or salt substitutes with potassium unless your doctor approves, because olmesartan can raise potassium.
• Use caution if you have kidney disease, liver disease, gout, diabetes, heart failure, or a history of angioedema.
• Alcohol may increase dizziness and low blood pressure.
• Be careful driving or using machinery until you know how Tri-Olmetor 40 Tablet affects you.
• Tell your doctor if you are pregnant or planning pregnancy; medicines that affect the renin-angiotensin system can harm an unborn baby.

• NSAIDs such as ibuprofen or naproxen may reduce blood pressure control and raise kidney risk.
• Lithium levels can rise when taken with this combination.
• Potassium supplements, potassium-sparing diuretics, or potassium salt substitutes may increase potassium too much.
• Other blood pressure medicines, including diuretics and vasodilators, can increase the risk of low blood pressure.
• Certain CYP3A4 inhibitors or inducers may affect amlodipine levels.

Store Tri-Olmetor 40 Tablet in its original strip/box at room temperature, away from moisture, heat, and direct light.