Triolmezest Tablet

Triolmezest Tablet is a prescription combination blood pressure medicine that contains olmesartan medoxomil, amlodipine, and hydrochlorothiazide in each tablet. It belongs to the ARB, calcium channel blocker, and thiazide diuretic drug classes. Triolmezest Tablet is used to treat high blood pressure in adults when a doctor feels that one medicine alone is not enough. Lowering blood pressure can help reduce the risk of stroke, heart attack, and kidney problems over time.

How it works: In Triolmezest Tablet, olmesartan relaxes blood vessels by blocking a hormone signal that tightens them, amlodipine relaxes the vessel walls directly, and hydrochlorothiazide helps the body remove extra salt and water. Taken together as a tablet, these three actions lower pressure inside the blood vessels and make it easier for the heart to pump.

Triolmezest Tablet is a higher-strength combination tablet, including the olmesartan medoxomil 40 mg strength sold in this brand family, so it is not the usual starting choice for every patient. It is typically selected for adults whose blood pressure has not been controlled well with lower-strength treatment or who need a more complete triple-medicine approach in one tablet.

• Treatment of high blood pressure in adults
• May be used when one or two blood pressure medicines are not enough
• Helps lower the risk of long-term complications from uncontrolled hypertension
• Doctor-directed maintenance therapy for blood pressure control

• Swallow Triolmezest Tablet whole with water; do not crush, chew, or split it unless your prescriber says to.
• Take it at the same time each day to help you remember your dose.
• It can be taken with or without food.
• If it makes you urinate more, many people prefer taking it earlier in the day.
• Stand up slowly after taking it, especially when starting treatment or after a dose change.
• Keep taking it even if you feel well, because high blood pressure often has no symptoms.

Triolmezest Tablet provides a fixed triple combination in each tablet, including olmesartan medoxomil 40 mg. The exact dosing schedule is individualized by the doctor; it is usually taken once daily, and the maximum daily amount is one tablet unless the prescriber specifically instructs otherwise.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Olmesartan Medoxomil + Amlodipine + Hydrochlorothiazide may include:

• Dizziness or lightheadedness
• Headache
• Swelling of the ankles or feet
• Tiredness or weakness
• Increased urination
• Nausea
• Lower blood pressure, which may be more noticeable with this higher-strength tablet

• Triolmezest Tablet can cause a bigger blood pressure drop in people who are dehydrated or already taking other blood pressure medicines.
• Use caution if you have kidney disease, liver disease, heart failure, or a history of low sodium or low potassium.
• This medicine may make you dizzy, so be careful driving or operating machinery until you know how it affects you.
• Alcohol can increase dizziness or lightheadedness.
• Do not use potassium supplements or salt substitutes unless your doctor says they are safe for you.
• Tell your doctor if you are pregnant or planning pregnancy; medicines that contain olmesartan are not used in pregnancy.
• Older adults may be more sensitive to the blood pressure-lowering and dehydrating effects of Triolmezest Tablet.

• NSAIDs such as ibuprofen or naproxen may reduce the blood pressure effect and can increase kidney risk.
• Other blood pressure medicines can add to dizziness or low blood pressure.
• Potassium supplements, potassium-sparing diuretics, or salt substitutes can raise potassium too much.
• Lithium levels can rise when taken with hydrochlorothiazide-containing products.
• Strong CYP3A4 inhibitors or inducers may affect amlodipine levels.

Store Triolmezest Tablet in its original strip or box at room temperature, away from moisture and excess heat, and keep it out of reach of children.