Triolmezest 40 Tablet

Triolmezest 40 Tablet is a prescription combination medicine used to help lower high blood pressure in adults. Each tablet contains olmesartan medoxomil 40 mg, amlodipine 5 mg, and hydrochlorothiazide 12.5 mg, so it combines an ARB, a calcium channel blocker, and a thiazide diuretic in one tablet. Triolmezest 40 Tablet is used when one medicine alone has not controlled blood pressure well enough, and it may also help reduce the risk of stroke, heart attack, and kidney problems related to long-term hypertension.

How it works: Olmesartan medoxomil helps relax blood vessels by blocking angiotensin II, a natural substance that tightens arteries. Amlodipine relaxes the muscle in blood vessel walls, and hydrochlorothiazide helps your body get rid of extra salt and water, so this tablet lowers pressure through three different actions.

Triolmezest 40 Tablet is a higher-strength fixed-dose tablet in this brand family, so it is usually chosen for adults who need stronger blood pressure control than lower-strength combinations can provide. Because it already contains three medicines at a set dose, it is not meant for starting treatment on your own; a doctor may choose Triolmezest 40 Tablet after checking your blood pressure response, fluid status, kidney function, and other medicines.

• Treatment of high blood pressure in adults
• Combination therapy when single medicines are not enough
• Blood pressure control to help lower long-term cardiovascular risk
• Supportive treatment in patients needing multi-drug antihypertensive therapy

• Take Triolmezest 40 Tablet by mouth with a glass of water.
• Swallow the tablet whole; do not crush, chew, or split it unless your doctor tells you to.
• Take it at the same time each day to help you remember.
• It can be taken with or without food.
• Stand up slowly after taking it, especially when you first start, because it may cause dizziness or lightheadedness.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.

Each Triolmezest 40 Tablet provides olmesartan medoxomil 40 mg + amlodipine 5 mg + hydrochlorothiazide 12.5 mg per tablet. The usual schedule is one tablet once daily, but your doctor may choose a different plan based on your blood pressure, kidney function, and how you respond. Do not take more than one tablet in 24 hours unless your prescriber specifically tells you to.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Olmesartan Medoxomil + Amlodipine + Hydrochlorothiazide may include:

• Dizziness or lightheadedness, especially when standing up
• Swelling of the ankles or feet
• Headache
• Fatigue or weakness
• Increased urination
• Nausea or stomach upset
• Low blood pressure symptoms, which may be more noticeable with this higher-strength tablet

• This is a stronger fixed-dose blood pressure tablet, so it should be used only if your doctor has decided you need this exact combination and strength.
• It can cause dehydration and low blood pressure, especially if you are older, on a low-salt diet, vomiting, or having diarrhea.
• Do not use potassium supplements or salt substitutes containing potassium unless your doctor says it is safe.
• Avoid alcohol or limit it, because it can worsen dizziness and low blood pressure.
• Use caution when driving or operating machinery until you know how Triolmezest 40 Tablet affects you.
• Tell your doctor if you have kidney disease, liver disease, gout, diabetes, or a history of angioedema.
• Do not use during pregnancy; medicines that affect the renin-angiotensin system can harm an unborn baby.

• Other blood pressure medicines, which can increase the risk of low blood pressure
• NSAIDs such as ibuprofen or naproxen, which may reduce blood pressure control and affect kidney function
• Potassium supplements or potassium-sparing diuretics, which may raise potassium too much
• Lithium, which may increase the risk of lithium toxicity
• Alcohol or medicines that cause drowsiness or dizziness, which can worsen lightheadedness

Store Triolmezest 40 Tablet at room temperature in its original strip or box, away from excess heat, moisture, and direct light.