Centri 400 mg/80 mg Tablet

Centri 400 mg/80 mg Tablet is a prescription antibiotic that contains sulfamethoxazole 400 mg and trimethoprim 80 mg in each tablet. It belongs to the sulfonamide antibiotic combination class and is used to treat certain bacterial infections, not viral illnesses like colds or flu. Centri 400 mg/80 mg Tablet may be prescribed for infections such as urinary tract infections, some ear or respiratory infections, and other susceptible bacterial infections when a doctor decides this strength is appropriate.

How it works: Sulfamethoxazole and trimethoprim work together by blocking two steps bacteria need to make folate, a nutrient they use to grow and multiply. In this tablet form, the two medicines are taken by mouth and absorbed into the body to help stop the bacterial infection from spreading.

Centri 400 mg/80 mg Tablet is a standard-strength tablet in the sulfamethoxazole/trimethoprim family, and it is often used when a doctor wants a smaller per-tablet amount than stronger tablet strengths. Because each tablet contains 400 mg/80 mg, it can be easier to fit into a prescribed schedule when the dose needs to be adjusted for the infection, age, kidney function, or overall tolerance.

• Urinary tract infections
• Certain ear infections
• Some respiratory tract infections
• Traveler’s diarrhea caused by susceptible bacteria
• Other doctor-diagnosed bacterial infections

• Swallow Centri 400 mg/80 mg Tablet with a full glass of water.
• Take it at the same time each day if your prescriber gives a regular schedule.
• You may take it with food or milk if it upsets your stomach.
• Drink plenty of fluids during treatment unless your doctor tells you to limit fluids.
• Do not crush or chew the tablet unless your pharmacist or doctor says it is safe to do so.
• Finish the full prescribed course even if you start feeling better.

Each Centri 400 mg/80 mg Tablet provides 400 mg of sulfamethoxazole and 80 mg of trimethoprim. How often it is taken depends on the infection and the prescriber’s plan; for this strength, some regimens use one tablet twice daily, while others may use different schedules, and the doctor sets the exact dose and duration. Do not take more than prescribed, because the maximum daily amount depends on the specific infection, your age, and kidney function.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sulfamethoxazole + Trimethoprim may include:

• Nausea
• Vomiting
• Loss of appetite
• Mild diarrhea
• Headache
• Rash or itching
• Sensitivity to sunlight

• Tell your doctor if you are allergic to sulfonamide antibiotics or trimethoprim.
• Use extra caution if you have kidney disease, liver disease, folate deficiency, or a history of blood disorders.
• This medicine may raise potassium levels, so it needs caution in people with heart disease or those taking medicines that affect potassium.
• Avoid heavy sun exposure and tanning beds because photosensitivity can occur.
• Limit alcohol if it worsens stomach upset or dizziness while taking this antibiotic.
• Tell your clinician if you are pregnant, trying to become pregnant, or breastfeeding.
• Do not use it for a viral infection, because Centri 400 mg/80 mg Tablet does not treat viruses.

• Warfarin and other blood thinners
• Methotrexate
• ACE inhibitors or ARBs, especially those that can raise potassium
• Spironolactone or other potassium-raising medicines
• Phenytoin and some diabetes medicines

Store Centri 400 mg/80 mg Tablet at room temperature in its original strip/box, away from moisture and excessive heat.