Oriprim 5 mL Eye Drop

Oriprim 5 mL Eye Drop is an antibiotic eye medicine containing sulfamethoxazole plus trimethoprim in a 5 mL ophthalmic dosage form. It belongs to the sulfonamide/folate-inhibitor antibiotic class and is used to treat certain bacterial eye infections when a prescriber decides it is appropriate. Oriprim 5 mL Eye Drop works only against bacteria, not viruses or allergies. Because it is a prescription antibiotic eye drop, it should be used exactly as directed for the eye condition being treated.

How it works: Sulfamethoxazole and trimethoprim work together by blocking two steps bacteria need to make folate, a vitamin-like substance they use to grow. As an eye drop, Oriprim 5 mL Eye Drop delivers this antibacterial action right to the eye surface to help clear the infection.

Oriprim 5 mL Eye Drop is a single ophthalmic strength and form, so there are no lower or higher sibling strengths in this product line to compare it with. The 5 mL bottle is typically chosen for local eye treatment, where the medicine can act directly at the site of infection rather than through the whole body. A doctor may choose this form when an eye-specific antibiotic effect is needed and wants the convenience of a small eye-drop bottle for short-term use.

• Bacterial conjunctivitis
• Bacterial blepharitis
• Other susceptible bacterial eye infections
• Doctor-directed treatment of eye surface infection

• Wash your hands before using Oriprim 5 mL Eye Drop.
• Tilt your head back, pull down the lower eyelid, and place the prescribed drop into the eye without touching the dropper tip.
• Close your eye gently for 1 to 2 minutes after dosing and press lightly at the inner corner if your doctor advises.
• Do not wear contact lenses during an active eye infection unless your prescriber says it is okay.
• If you use other eye medicines, wait at least 5 to 10 minutes between products unless told otherwise.
• Use the bottle for the full course prescribed, even if the eye feels better sooner.

The strength for this product is a 5 mL eye-drop bottle; the exact number of drops per dose depends on how your doctor prescribes it and how the bottle is used. Eye-drop dosing is usually prescribed several times a day for a set number of days, and there is no universal maximum daily amount because the prescriber individualizes the schedule. Follow the doctor’s directions exactly for Oriprim 5 mL Eye Drop, since the right dose depends on the type and severity of the eye infection.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sulfamethoxazole + Trimethoprim may include:

• Temporary eye stinging or burning
• Mild eye irritation
• Blurred vision right after dosing
• Watery eyes
• Redness or itching at the application site
• Unpleasant taste in the mouth after the drop drains into the nose/throat

• Do not use Oriprim 5 mL Eye Drop if you have a known allergy to sulfonamides or trimethoprim unless your doctor specifically says otherwise.
• Tell your doctor if you have a history of severe skin reactions, blood disorders, liver disease, kidney disease, or folate deficiency.
• Remove contact lenses before use and ask when it is safe to put them back in.
• Use caution when driving right after dosing because temporary blurred vision can happen.
• Do not use this eye drop for viral, fungal, or allergic eye problems.
• Tell your prescriber if you are pregnant, breastfeeding, or using it for a child.
• Do not share the bottle with anyone else, even if they have similar symptoms.

• Other eye medicines or ointments, which may need to be spaced apart
• Warfarin and other blood thinners
• Methotrexate
• Oral diabetes medicines that can lower blood sugar
• ACE inhibitors or ARBs, especially if there is kidney disease

Store Oriprim 5 mL Eye Drop at room temperature and keep the bottle tightly closed; do not freeze it and discard it after the opening period or expiration date given on the label.