Co Trimoxazole SS 400 mg/80 mg Tablet

Co Trimoxazole SS 400 mg/80 mg Tablet is a prescription antibiotic that contains sulfamethoxazole 400 mg and trimethoprim 80 mg in each tablet. It belongs to the sulfonamide antibiotic combination class and is used to treat certain bacterial infections, not viruses like the common cold or flu. This Co Trimoxazole SS 400 mg/80 mg Tablet is used when a clinician wants the fixed-dose sulfamethoxazole + trimethoprim combination in tablet form for an appropriate infection.

How it works: In Co Trimoxazole SS 400 mg/80 mg Tablet, sulfamethoxazole and trimethoprim work together to block two steps bacteria need to make folate, a vitamin-like substance they need to grow. By stopping bacterial growth, this tablet helps the body clear the infection.

Co Trimoxazole SS 400 mg/80 mg Tablet is the single-strength tablet, so it provides half the amount of active ingredients found in a double-strength 800 mg/160 mg tablet. Because it is a lower-strength tablet, it may be chosen when a doctor wants smaller individual doses, adjusted dosing, or a regimen that uses more tablets spread through the day. It is not a starting strength for every infection; the right dose depends on the infection being treated and the patient’s medical history.

• Urinary tract infections
• Certain ear, bronchial, or respiratory bacterial infections
• Traveler’s diarrhea caused by susceptible bacteria
• Some skin and soft tissue infections
• Prevention or treatment of specific opportunistic infections when prescribed

• Swallow the Co Trimoxazole SS 400 mg/80 mg Tablet whole with a full glass of water.
• Take it exactly as prescribed, at evenly spaced times, and finish the full course even if you feel better.
• It may be taken with food or milk if it upsets your stomach.
• Drink plenty of fluids while taking this tablet unless your doctor has told you to limit fluids.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.

Each Co Trimoxazole SS 400 mg/80 mg Tablet provides sulfamethoxazole 400 mg plus trimethoprim 80 mg. Depending on the infection, this tablet may be taken once, twice, or several times daily, but the exact schedule is determined by the doctor. The maximum daily amount varies by condition and patient factors, so do not change the dose on your own.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sulfamethoxazole + Trimethoprim may include:

• Nausea
• Vomiting
• Loss of appetite
• Mild diarrhea
• Headache
• Dizziness
• Skin rash or itching

• Do not use Co Trimoxazole SS 400 mg/80 mg Tablet if you have a sulfa allergy or have had a serious reaction to trimethoprim-sulfamethoxazole before unless your doctor specifically approves it.
• Tell your doctor if you have kidney disease, liver disease, folate deficiency, or are prone to dehydration, because this tablet can require extra caution.
• Drink enough water during treatment to help reduce the risk of kidney-related side effects.
• This medicine can make your skin more sensitive to sunlight, so use sun protection and avoid prolonged tanning or sun exposure.
• Tell your clinician if you are pregnant, planning pregnancy, or breastfeeding, because this combination may not be appropriate in some situations.
• Use caution with driving or operating machinery if you feel dizzy or unwell after taking the tablet.
• Seek medical advice promptly if you develop fever, sore throat, mouth sores, or a new rash while taking this antibiotic.

• Warfarin and other blood thinners
• ACE inhibitors, ARBs, and potassium-sparing diuretics, which can raise potassium
• Methotrexate
• Digoxin
• Phenytoin

Store Co Trimoxazole SS 400 mg/80 mg Tablet in its original strip/box at room temperature, away from moisture, heat, and direct light.