Septran 400 + 80 mg Tablet

Septran 400 + 80 mg Tablet is an oral antibiotic tablet that contains sulfamethoxazole 400 mg and trimethoprim 80 mg in each tablet. It belongs to the sulfonamide/antifolate antibiotic class and is used to treat certain bacterial infections. Doctors prescribe Septran 400 + 80 mg Tablet for infections such as some urinary tract, ear, bronchial, and intestinal infections when the bacteria are likely to respond to this combination. It is not for colds, flu, or other viral infections.

How it works: Sulfamethoxazole and trimethoprim work together by blocking two different steps bacteria need to make folic acid, which helps them grow and multiply. In tablet form, Septran 400 + 80 mg Tablet is swallowed so the medicine can be absorbed into the body and reach the infection site through the bloodstream.

Septran 400 + 80 mg Tablet is the standard-strength tablet in this brand, and in our range there are no lower or higher strengths of this product. That means the prescriber uses this tablet to build a complete dose based on the infection being treated and the patient’s age, weight, kidney function, and other health factors. It is a regular-strength antibiotic tablet rather than a fast-acting pain reliever, so the goal is steady treatment over the prescribed course, not immediate symptom relief.

• Urinary tract infections
• Certain ear infections
• Some bronchitis and respiratory infections
• Traveler’s diarrhea due to susceptible bacteria
• Other bacterial infections as prescribed by a doctor

• Swallow Septran 400 + 80 mg Tablet with a full glass of water.
• Take it exactly as prescribed; the dose schedule can vary by infection and patient factors.
• You may take it with food or milk if it upsets your stomach.
• Drink plenty of fluids during treatment unless your doctor tells you to limit fluids.
• Finish the full prescribed course even if you start feeling better.
• Do not take extra tablets to make up for a missed dose unless your prescriber tells you to.

Each Septran 400 + 80 mg Tablet provides 80 mg trimethoprim with 400 mg sulfamethoxazole in one tablet. How many tablets you take and how often you take them depends on the infection being treated and your doctor’s instructions; for some infections it may be taken once or twice daily, while other regimens use different schedules. Do not exceed the daily amount prescribed by your clinician, because the correct maximum dose for this strength depends on the indication and your individual health status.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sulfamethoxazole + Trimethoprim may include:

• Nausea
• Vomiting
• Loss of appetite
• Mild diarrhea
• Headache
• Rash or itching
• Increased sensitivity to sunlight

• Tell your doctor if you have a sulfa allergy or have reacted to trimethoprim-sulfamethoxazole before.
• Use caution if you have kidney disease, liver disease, folate deficiency, or a history of blood disorders.
• This antibiotic can increase sun sensitivity, so limit sun exposure and use protection outdoors.
• Stay well hydrated to reduce the risk of kidney-related side effects, unless fluid restriction has been advised.
• Let your clinician know if you take medicines for diabetes, seizures, blood pressure, or blood thinners.
• Avoid alcohol if it worsens stomach upset or dizziness while taking the tablet.
• Seek medical advice before use if you are pregnant, planning pregnancy, or breastfeeding.

• Warfarin and other blood thinners
• Methotrexate
• ACE inhibitors or ARBs and potassium-sparing diuretics
• Sulfonylurea diabetes medicines
• Phenytoin and some other seizure medicines

Store Septran 400 + 80 mg Tablet in its original strip/box at room temperature, away from moisture and excessive heat.