Trimazole DS 800 mg/160 mg Tablet

Trimazole DS 800 mg/160 mg Tablet is a prescription antibiotic tablet that contains sulfamethoxazole 800 mg and trimethoprim 160 mg in each tablet. It belongs to the sulfonamide antibiotic combination class, often called co-trimoxazole or TMP-SMX. Doctors use Trimazole DS 800 mg/160 mg Tablet to treat certain bacterial infections, including some urinary tract, respiratory, ear, intestinal, and skin infections, when the bacteria are likely to respond to this combination.

How it works: Trimazole DS 800 mg/160 mg Tablet works by combining two antibiotics that block bacteria from making folate, which they need to grow and multiply. Taken as a tablet, it is absorbed through the stomach and intestines and then circulates through the body to help clear susceptible bacterial infections.

Trimazole DS 800 mg/160 mg Tablet is the double-strength tablet, so each dose delivers a higher amount of both antibiotics than a standard-strength tablet would. This strength is often chosen for infections that need stronger treatment or for adults and older adolescents who can take a higher-dose tablet as directed by a clinician. Because it is a higher-strength tablet, it should be used only when a doctor has decided this exact dose is appropriate.

• Urinary tract infections
• Certain respiratory infections
• Ear infections
• Traveler's diarrhea caused by susceptible bacteria
• Some skin and soft tissue infections

• Swallow Trimazole DS 800 mg/160 mg Tablet whole with a full glass of water.
• Take it exactly as prescribed, at evenly spaced times if your doctor tells you to take it more than once daily.
• You may take it with food or milk if it upsets your stomach.
• Drink plenty of fluids during treatment unless your doctor has told you to restrict fluids.
• Do not crush or split the tablet unless your pharmacist or doctor specifically says it is safe to do so.
• Finish the full course even if you start to feel better before it is gone.

Each Trimazole DS 800 mg/160 mg Tablet provides sulfamethoxazole 800 mg plus trimethoprim 160 mg. This higher-strength tablet may be taken once or twice daily for many infections, but the exact schedule depends on the infection being treated, kidney function, and other patient factors. The maximum daily amount is determined by the prescriber, so do not take extra tablets or change the schedule on your own.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sulfamethoxazole + Trimethoprim may include:

• Nausea
• Vomiting
• Loss of appetite
• Mild diarrhea
• Headache
• Rash or itching
• Increased sensitivity to sunlight

• Trimazole DS 800 mg/160 mg Tablet can cause serious allergic reactions in people allergic to sulfonamide antibiotics.
• This higher-strength tablet may be more likely to cause stomach upset or other dose-related side effects if taken more often than prescribed.
• Tell your doctor if you have kidney disease, liver disease, folate deficiency, or a history of blood disorders.
• Use caution with sun exposure because this medicine can make you more sensitive to sunlight.
• People with G6PD deficiency may have a higher risk of hemolysis with this medicine.
• This antibiotic can interact with medicines that raise potassium, such as ACE inhibitors, ARBs, or spironolactone.
• Avoid driving or hazardous activities if you feel dizzy or unwell after taking the tablet.

• Warfarin and other blood thinners
• ACE inhibitors, ARBs, and potassium-sparing diuretics
• Methotrexate
• Phenytoin
• Digoxin

Store Trimazole DS 800 mg/160 mg Tablet in its original strip or box at room temperature, away from moisture, heat, and direct light.