Supristol 400 mg/80 mg Tablet

Supristol 400 mg/80 mg Tablet is an antibiotic tablet that contains sulfamethoxazole 400 mg and trimethoprim 80 mg in each dose. It belongs to the sulfonamide antibiotic combination class and is used to treat certain bacterial infections when this medicine is appropriate for the germ causing the illness. This specific Supristol 400 mg/80 mg Tablet is a standard-strength tablet, not a chewable or liquid form, and it is taken by mouth as directed by a clinician.

How it works: Sulfamethoxazole and trimethoprim work together to block two steps bacteria need to make folic acid, which helps stop the bacteria from growing. In this tablet form, the two medicines are absorbed after swallowing and start working through the bloodstream against susceptible bacteria.

Supristol 400 mg/80 mg Tablet provides the classic 400 mg/80 mg tablet strength used in common adult and adolescent treatment plans. Because there are no other strengths or forms listed for this brand here, this tablet is the exact form your doctor may choose when a standard oral tablet dose is needed and the patient can swallow tablets. It is not a higher-strength product; it fits typical dosing schedules for this antibiotic combination.

• Urinary tract infections
• Ear infections caused by susceptible bacteria
• Certain respiratory tract infections
• Traveler’s diarrhea caused by susceptible bacteria
• Some skin and soft tissue infections

• Swallow the Supristol 400 mg/80 mg Tablet with a full glass of water.
• Take it exactly at the times prescribed; doses are often spaced evenly through the day.
• You may take it with food or milk if it upsets your stomach.
• Drink plenty of fluids while taking this medicine unless your doctor tells you to limit fluids.
• Do not crush or split the tablet unless your pharmacist or prescriber says it is okay.
• Finish the full course even if you start to feel better, unless your doctor tells you to stop.

Each Supristol 400 mg/80 mg Tablet provides 400 mg of sulfamethoxazole plus 80 mg of trimethoprim. The dose may be taken once or several times a day depending on the infection, but the exact schedule and maximum daily amount must be set by your doctor. This tablet strength is commonly used in standard divided-dose regimens, so the prescribed number of tablets per day depends on the infection and your medical history.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sulfamethoxazole + Trimethoprim may include:

• Nausea
• Loss of appetite
• Vomiting
• Diarrhea
• Mild rash
• Headache
• Increased sensitivity to sunlight

• Do not use if you have a known sulfonamide allergy or had a serious reaction to trimethoprim-sulfamethoxazole before.
• Use caution if you have kidney disease, liver disease, anemia, folate deficiency, or a history of low platelets.
• Stay well hydrated because this antibiotic can sometimes affect the kidneys and may cause crystalluria in some people.
• This medicine can make your skin more sensitive to sunlight, so use sun protection and avoid excessive UV exposure.
• Tell your doctor if you take blood thinners, diabetes medicines, ACE inhibitors, or ARBs because this tablet can raise the risk of certain adverse effects.
• Alcohol is not a direct contraindication, but it can worsen stomach upset and dehydration while you are sick.
• Contact a clinician promptly if you develop fever, sore throat, or a new rash, since rare but serious blood or skin reactions can occur.

• Warfarin and other blood thinners
• Methotrexate
• ACE inhibitors or ARBs such as lisinopril or losartan
• Spironolactone
• Pyrimethamine or other medicines that may lower folate

Store Supristol 400 mg/80 mg Tablet at room temperature in its original strip or box, away from moisture and heat.