Seroflo 125 Synchrobreathe

Seroflo 125 Synchrobreathe is a combination asthma inhaler containing salmeterol and fluticasone propionate, with 125 mcg of fluticasone propionate in each actuation as labeled. It belongs to the long-acting beta2-agonist (LABA) plus inhaled corticosteroid class and is used to help control asthma symptoms and reduce flare-ups. Seroflo 125 Synchrobreathe is for maintenance treatment, not for quick relief of sudden wheezing or shortness of breath.

How it works: Salmeterol helps keep the airways open for many hours by relaxing the muscles around the breathing tubes. Fluticasone propionate lowers swelling and irritation inside the airways, and together in Seroflo 125 Synchrobreathe they help prevent asthma symptoms when used regularly.

Seroflo 125 Synchrobreathe is a mid-strength option and is generally chosen for people whose asthma is not controlled with a lower-dose inhaled steroid/LABA combination. Compared with Seroflo Ecopack 250 Inhaler, this strength delivers less fluticasone propionate per dose, so it may be a better fit when a prescriber wants steroid exposure kept lower while still providing maintenance control. A clinician may choose Seroflo 125 Synchrobreathe based on symptom severity, prior inhaler response, and side effect risk.

• Maintenance treatment of asthma
• Prevention of wheezing and chest tightness
• Reduction of nighttime asthma symptoms
• Help lowering the risk of asthma flare-ups
• Long-term control in patients who need both a steroid and a LABA

• Use Seroflo 125 Synchrobreathe exactly as your doctor prescribed; it is not a rescue inhaler.
• This is an inhaler, not a tablet: inhale the medicine into the lungs rather than swallowing it.
• Breathe out fully before using the inhaler, then seal your lips around the mouthpiece and inhale deeply and steadily.
• Hold your breath for as long as comfortable after inhaling to help the medicine reach the airways.
• Rinse your mouth with water and spit it out after each dose to lower the risk of oral thrush.
• Use it at the same times each day, and do not take extra doses unless your prescriber tells you to.

Seroflo 125 Synchrobreathe provides 125 mcg of fluticasone propionate per inhalation, along with salmeterol in the fixed-dose combination. The exact number of inhalations and how often to use it depends on the prescriber’s plan; it is typically used on a regular schedule, not for sudden symptoms, and the maximum daily inhalations should not be exceeded. Your doctor decides whether Seroflo 125 Synchrobreathe is the right strength for you and whether a lower or higher strength is needed.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Salmeterol + Fluticasone Propionate may include:

• Hoarseness or voice changes
• Sore throat or throat irritation
• Oral thrush (white patches in the mouth)
• Headache
• Tremor or jitteriness
• Increased heart rate or palpitations
• Cough after inhalation

• Seroflo 125 Synchrobreathe is for asthma control only and should not be used to treat a sudden attack.
• Because this is a combination inhaler with a steroid and a LABA, use only the dose your doctor prescribes; extra use can raise the risk of side effects.
• Tell your doctor if you have heart disease, high blood pressure, irregular heartbeat, diabetes, thyroid disease, seizures, or glaucoma.
• Use caution if you are taking a strong CYP3A4 inhibitor, because steroid levels can rise and increase side effects.
• Rinse and spit after each use to help prevent mouth thrush.
• Do not stop Seroflo 125 Synchrobreathe suddenly without medical advice, especially if you have been using it regularly.
• If your asthma is getting worse or you need your rescue inhaler more often, contact your prescriber promptly.

• Strong CYP3A4 inhibitors such as ketoconazole, ritonavir, or cobicistat
• Other LABA-containing inhalers or asthma medicines that duplicate salmeterol
• Beta-blockers, including some eye drops, which can reduce bronchodilator effect
• Diuretics or other medicines that can lower potassium
• MAO inhibitors or tricyclic antidepressants, which may increase cardiovascular effects

Store Seroflo 125 Synchrobreathe at room temperature in the original strip/box, away from moisture, heat, and direct sunlight.