Seroflo Rotacaps 50 mcg + 500 mcg

Seroflo Rotacaps 50 mcg + 500 mcg is a prescription inhaled medicine used for the long-term control of asthma. Each rotacap contains salmeterol 50 mcg and fluticasone propionate 500 mcg, a combination of a long-acting bronchodilator and an inhaled corticosteroid. It helps reduce airway inflammation and keep the airways open, lowering the chance of wheezing, chest tightness, and shortness of breath. Seroflo Rotacaps 50 mcg + 500 mcg is not a rescue inhaler for sudden asthma attacks.

How it works: Salmeterol relaxes the muscles around the airways for long-acting opening of the lungs, while fluticasone propionate reduces swelling and mucus inside the airways. In the rotacap form, the powder is inhaled into the lungs through the appropriate device, where both ingredients act locally to help prevent asthma symptoms.

Seroflo Rotacaps 50 mcg + 500 mcg is the highest-strength version sold here, so it is meant for people whose asthma has already been assessed by a doctor and who need a stronger maintenance dose of fluticasone propionate with the same 50 mcg salmeterol base. Compared with lower-strength Seroflo Rotacaps, this strength delivers more anti-inflammatory medicine in each capsule, which may be chosen when symptoms are not adequately controlled with lower doses.

• Maintenance treatment of asthma
• Prevention of wheezing and breathlessness
• Reduction of airway inflammation
• Long-term control in patients who need a higher inhaled steroid dose

• Use Seroflo Rotacaps 50 mcg + 500 mcg only with the rotacap inhaler device, not by swallowing the capsule whole.
• Remove one rotacap from the strip or box of 10 capsules only when you are ready to inhale it.
• Place the capsule in the device and pierce it as directed, then inhale the powder deeply and steadily.
• Do not chew, crush, or open the capsule outside the inhaler.
• Use it at the same times each day as prescribed; it is not for quick relief before an acute asthma attack.
• Rinse your mouth with water and spit it out after inhalation to reduce the risk of thrush.

Each Seroflo Rotacaps 50 mcg + 500 mcg capsule provides salmeterol 50 mcg plus fluticasone propionate 500 mcg. The usual schedule for this type of maintenance inhaler is often twice daily, but the exact dose and frequency must be set by the doctor based on asthma severity and response. Do not take more than prescribed, and do not use extra capsules for sudden symptoms.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Salmeterol + Fluticasone Propionate may include:

• Hoarseness or voice changes
• Throat irritation
• Cough after inhalation
• Oral thrush (more likely if the mouth is not rinsed after use)
• Headache
• Mild tremor or shakiness
• Fast heartbeat or palpitations

• Seroflo Rotacaps 50 mcg + 500 mcg is not a rescue medicine; keep a fast-acting inhaler for sudden asthma symptoms if prescribed.
• Because this is the 500 mcg fluticasone strength, it should be used only when a clinician has decided a higher inhaled steroid dose is appropriate.
• Tell your doctor if you have heart disease, high blood pressure, diabetes, thyroid disease, seizures, or low potassium.
• Use caution if you are taking medicines that can lower potassium or affect the heart rhythm.
• After each dose, rinse and spit to lower the risk of oral thrush.
• Do not stop this medicine suddenly unless your prescriber tells you to.
• If you have had tuberculosis, eye disease such as glaucoma or cataracts, or frequent infections, your doctor should know before use.

• Strong CYP3A4 inhibitors such as ritonavir, cobicistat, ketoconazole, or itraconazole may increase steroid exposure.
• Other long-acting beta-agonists or asthma combination inhalers can increase side effects if used together.
• Beta-blockers may reduce the bronchodilator effect and can worsen asthma.
• Diuretics or other medicines that lower potassium may increase the risk of low potassium and heart rhythm problems.

Store Seroflo Rotacaps 50 mcg + 500 mcg in the original strip/box at room temperature, protected from moisture and heat, and keep the capsules dry until use.