Alsita M 50 mg/500 mg Tablet ER

Alsita M 50 mg/500 mg Tablet ER is an extended-release prescription medicine that combines sitagliptin 50 mg and metformin 500 mg in each tablet. It belongs to the diabetes medicines class and is used along with diet and exercise to help improve blood sugar control in adults with type 2 diabetes. The metformin component helps reduce glucose made by the liver, while sitagliptin helps the body increase insulin release after meals.

How it works: Sitagliptin helps your body release more insulin when blood sugar is high and lowers the amount of sugar your liver and intestines add to the bloodstream after meals. Metformin in this tablet helps your body use insulin better and reduces sugar production by the liver, which is why Alsita M 50 mg/500 mg Tablet ER is taken as an oral tablet for type 2 diabetes.

Alsita M 50 mg/500 mg Tablet ER is a higher-strength combination tablet, so it is generally used for people whose diabetes control needs both sitagliptin and metformin in this specific dose. Because it is an ER tablet, it is designed for slower release over time, which may help with steadier blood sugar control and once-daily or twice-daily scheduling depending on the prescriber’s plan. Since there are no other listed strengths or forms in this brand line, this tablet is the exact product your clinician would choose based on your current treatment needs and kidney function.

• Type 2 diabetes mellitus
• Improving blood sugar control
• Used with diet and exercise
• Combination therapy when one medicine is not enough

• Swallow the Alsita M 50 mg/500 mg Tablet ER whole with water; do not crush, split, or chew the extended-release tablet.
• Take it exactly as prescribed, usually with food to help reduce stomach upset from metformin.
• Take it at the same time each day if your doctor has set a regular schedule.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.
• Check your blood sugar as directed and follow your meal plan while taking this tablet.

Each Alsita M 50 mg/500 mg Tablet ER contains sitagliptin 50 mg and metformin 500 mg. The dose may be taken once daily or in some cases as directed by a doctor in a divided schedule, but the exact frequency and the maximum daily amount must be set by the prescriber based on kidney function, blood sugar response, and other medicines. Do not increase the number of tablets on your own, because this strength already contains a meaningful metformin dose and a full 50 mg of sitagliptin per tablet.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sitagliptin + Metformin may include:

• Diarrhea, which is a common metformin effect
• Nausea or vomiting
• Stomach pain or gas
• Headache
• Upper respiratory symptoms such as runny nose or sore throat
• Low appetite or metallic taste

• Not for type 1 diabetes or diabetic ketoacidosis
• Use caution if you have kidney disease, because metformin dosing depends on kidney function
• Avoid heavy alcohol use, which can raise the risk of lactic acidosis
• Tell your doctor if you have a history of pancreatitis or gallbladder problems
• Get medical advice before using if you have heart failure, liver disease, or severe dehydration
• Do not drive if you feel dizzy or weak from low blood sugar
• This 50 mg/500 mg strength may be more than a starting dose for some patients, so it should only be used under medical supervision

• Insulin and sulfonylureas may increase the risk of low blood sugar
• Alcohol can increase the risk of serious metformin-related side effects
• Iodinated contrast dye used for some scans may require temporary stopping of metformin-containing medicines
• Certain diuretics, steroids, or other diabetes medicines can change blood sugar levels
• Cimetidine and some other medicines may affect metformin clearance

Store Alsita M 50 mg/500 mg Tablet ER at room temperature in the original strip/box, away from excess heat, moisture, and light.