Mesazed 400 mg Tablet

Mesazed 400 mg Tablet is a prescription medicine containing 400 mg of mesalazine (also called mesalamine) in each tablet. It belongs to the aminosalicylate class of medicines and is used to help treat and maintain remission in ulcerative colitis and other inflammatory bowel conditions involving the colon, as directed by a doctor. Mesazed 400 mg Tablet is made by Leeford Healthcare Limited and comes as a strip/box of 10 tablets. It works in the gut to reduce inflammation rather than relieving symptoms instantly.

How it works: Mesalazine helps calm inflammation in the lining of the intestine, especially the colon, where ulcerative colitis causes damage and symptoms. As a tablet, Mesazed 400 mg Tablet releases mesalamine after swallowing so the medicine can act locally in the bowel.

Mesazed 400 mg Tablet is a moderate-strength mesalazine tablet that can help doctors tailor treatment when smaller strengths are not enough or when a specific total daily dose is needed. Because it is a 400 mg tablet, it may be used as part of a higher total daily regimen spread across the day, which can improve dose flexibility for adults and selected patients. Your doctor chooses this strength based on your condition, response, and how many tablets per day are appropriate for you.

• Ulcerative colitis
• Maintenance of remission in inflammatory bowel disease
• Reduction of bowel inflammation
• Doctor-directed treatment of colonic inflammation

• Swallow Mesazed 400 mg Tablet whole with water unless your doctor tells you otherwise.
• Take it exactly at the times prescribed; do not change the schedule on your own.
• You can take it with or without food unless your prescriber gives different instructions.
• Do not crush, split, or chew the tablet unless the label or pharmacist says it is safe for your specific product.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.
• Drink enough fluids while taking this medicine, especially if your doctor has advised long-term use.

Each Mesazed 400 mg Tablet provides 400 mg of mesalazine. The total dose may be taken once daily or divided into multiple doses depending on the condition being treated, but the exact schedule and maximum daily amount must be set by the doctor. Because this is a 400 mg strength, many patients will take more than one tablet per dose or per day to reach the prescribed total amount.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Mesalazine / Mesalamine may include:

• Headache
• Nausea
• Abdominal pain
• Diarrhea
• Gas or bloating
• Vomiting
• Rash or itching

• Tell your doctor if you have kidney disease, liver disease, or a history of kidney stones before using Mesazed 400 mg Tablet.
• Use extra caution if you have aspirin allergy or have reacted to salicylates or other mesalamine products before.
• This medicine is for doctor-directed use in inflammatory bowel disease and is not meant for sudden severe abdominal pain without evaluation.
• Let your clinician know about pregnancy or breastfeeding before starting treatment.
• Report any change in urine output, swelling, or unexplained fatigue right away, as kidney effects can occur.
• Do not start or stop NSAIDs, blood thinners, or other bowel medicines without checking with your prescriber.
• Avoid dehydration and discuss alcohol use with your doctor, especially if you have stomach irritation or liver concerns.

• Azathioprine or 6-mercaptopurine
• Warfarin and other anticoagulants
• NSAIDs such as ibuprofen or naproxen
• Other mesalazine/mesalamine products
• Medicines that may affect kidney function

Store Mesazed 400 mg Tablet at room temperature in a dry place, away from moisture and direct heat, and keep it out of reach of children.