Oriprim DS 800 mg/160 mg Tablet

Oriprim DS 800 mg/160 mg Tablet is a prescription antibiotic tablet that contains sulfamethoxazole 800 mg and trimethoprim 160 mg in each tablet. It belongs to the sulfonamide antibiotic combination class and is used to treat certain bacterial infections, not viral illnesses like colds or flu. This Oriprim DS 800 mg/160 mg Tablet is commonly chosen when a stronger, double-strength tablet is appropriate for the infection being treated. It should be used only when a clinician decides this specific strength is right for you.

How it works: Sulfamethoxazole and trimethoprim work together by blocking two steps bacteria need to make folate, a vitamin-like substance they use to grow and multiply. As a tablet, Oriprim DS 800 mg/160 mg is swallowed so the medicines can be absorbed and circulate through the body to reach the infection.

The Oriprim DS 800 mg/160 mg Tablet is the double-strength tablet, so each dose delivers more sulfamethoxazole and trimethoprim than lower-strength tablets. Because of that, it may be selected for adults and other patients who need a higher per-tablet antibiotic dose and can safely take it as prescribed; it is not a starting strength to self-adjust. Some people may notice the effects and side effects more noticeably at this higher strength, so a doctor may choose it to match the infection and the dosing schedule.

• Urinary tract infections
• Certain skin infections
• Some respiratory tract infections
• Ear infections in selected cases
• Other susceptible bacterial infections as prescribed

• Swallow the Oriprim DS 800 mg/160 mg Tablet whole with a full glass of water.
• Take it exactly on the schedule your doctor prescribes, often twice daily for many infections.
• You may take this tablet with food or milk if it upsets your stomach.
• Drink enough fluids during treatment unless your doctor tells you to limit fluids.
• Finish the full prescribed course even if you start feeling better.
• Do not crush or chew the tablet unless your pharmacist or doctor specifically tells you to.

Each Oriprim DS 800 mg/160 mg Tablet provides sulfamethoxazole 800 mg plus trimethoprim 160 mg. The tablet is often taken every 12 hours, but the exact dose, frequency, and length of treatment depend on the infection, your age, kidney function, and other medical factors. Do not take more than prescribed; your doctor decides whether this higher-strength tablet and a twice-daily schedule are appropriate for you.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sulfamethoxazole + Trimethoprim may include:

• Nausea
• Vomiting
• Loss of appetite
• Mild diarrhea
• Headache
• Rash or itching
• Increased sensitivity to sunlight, which may be more noticeable at this double-strength dose

• Do not use if you have a known sulfonamide or trimethoprim allergy.
• This 800 mg/160 mg tablet is a higher-strength antibiotic, so take only the dose your clinician prescribed.
• Tell your doctor if you have kidney disease, liver disease, folate deficiency, or a history of blood disorders.
• Stay hydrated and report reduced urine output, since this medicine can affect the kidneys in some people.
• Use extra sun protection because photosensitivity can occur.
• Ask your clinician before using if you are pregnant, trying to become pregnant, or breastfeeding.
• Use caution with driving if you feel dizzy or unwell after taking the tablet.

• Warfarin and other blood thinners
• ACE inhibitors, ARBs, or potassium-sparing diuretics, which may raise potassium
• Methotrexate
• Phenytoin
• Dofetilide

Store Oriprim DS 800 mg/160 mg Tablet in its original strip/box at room temperature, away from moisture, heat, and direct light.