Sepnil 400 mg/80 mg Tablet

Sepnil 400 mg/80 mg Tablet is a prescription antibiotic that contains sulfamethoxazole 400 mg and trimethoprim 80 mg in each tablet. It belongs to the sulfonamide antibiotic combination class and is used to treat certain bacterial infections, not viral illnesses like colds or flu. Doctors may prescribe Sepnil 400 mg/80 mg Tablet for infections such as some urinary tract, ear, respiratory, and intestinal infections when the bacteria are likely to respond to this medicine.

How it works: This tablet combines two antibiotics that block different steps bacteria need to make folate, a vitamin-like substance they need to grow and multiply. By stopping bacterial growth in two ways, Sepnil 400 mg/80 mg Tablet helps the immune system clear the infection.

Sepnil 400 mg/80 mg Tablet is the standard single-tablet strength of sulfamethoxazole/trimethoprim used for many adult treatment plans, so it may be chosen when a prescriber wants a familiar, flexible dose. Because there are no other Sepnil strengths or forms listed here, this tablet is the product available for dose adjustment by the doctor based on the infection, age, kidney function, and response to treatment.

• Urinary tract infections
• Certain ear infections
• Some respiratory tract infections
• Traveler's diarrhea caused by susceptible bacteria
• Other bacterial infections as prescribed

• Swallow the tablet whole with a full glass of water.
• Take Sepnil 400 mg/80 mg Tablet exactly as prescribed, at evenly spaced times.
• You may take it with food or milk if it upsets your stomach.
• Drink plenty of fluids while taking this medicine unless your doctor tells you to limit fluids.
• Finish the full course even if you start to feel better.
• Do not crush or chew unless your pharmacist or doctor specifically tells you it is okay.

Each Sepnil 400 mg/80 mg Tablet provides 400 mg sulfamethoxazole plus 80 mg trimethoprim. Depending on the infection, doctors may prescribe it once or twice daily, and the exact schedule and maximum daily dose are based on the condition being treated, your age, and kidney function. Do not self-adjust the dose, because this strength should be used only as directed by a clinician.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sulfamethoxazole + Trimethoprim may include:

• Nausea
• Vomiting
• Loss of appetite
• Mild diarrhea
• Headache
• Skin rash or itching
• Increased sensitivity to sunlight

• Tell your doctor if you have a sulfa allergy or a previous bad reaction to sulfamethoxazole or trimethoprim.
• Use caution if you have kidney disease, liver disease, folate deficiency, or a history of blood disorders.
• This medicine can raise potassium levels, so extra caution is needed if you take potassium-raising drugs or have kidney problems.
• Avoid excessive sun exposure and tanning beds because Sepnil 400 mg/80 mg Tablet can make your skin more sensitive to sunlight.
• Drink enough water to help lower the risk of kidney-related side effects, unless fluid restriction has been prescribed.
• Tell your clinician if you are pregnant, planning pregnancy, or breastfeeding, because this antibiotic may not be appropriate in some situations.
• Do not use it for viral infections, and do not skip doses or stop early unless your doctor tells you to.

• Warfarin and other blood thinners
• Methotrexate
• ACE inhibitors or ARBs that can increase potassium
• Spironolactone or other potassium-sparing diuretics
• Phenytoin

Store Sepnil 400 mg/80 mg Tablet at room temperature in the original strip or box, away from moisture, heat, and direct light.