Ibiflo-S 250 Nexhaler

Ibiflo-S 250 Nexhaler is a prescription asthma medicine that combines salmeterol, a long-acting bronchodilator, with fluticasone propionate, an inhaled corticosteroid. Each Ibiflo-S 250 Nexhaler tablet is labeled as 250 strength and is used to help prevent and control asthma symptoms over time. It is not a rescue medicine for sudden breathing problems. Doctors choose this type of combination treatment when daily anti-inflammatory control and longer-lasting airway opening are both needed.

How it works: Salmeterol relaxes the muscles around the airways so air can move more easily, while fluticasone propionate reduces airway swelling and irritation. In tablet form, Ibiflo-S 250 Nexhaler is intended for maintenance use to help keep asthma symptoms from flaring up.

Ibiflo-S 250 Nexhaler is a higher-strength presentation of this salmeterol/fluticasone product, so it is generally suited for patients whose asthma is not well controlled on lower-strength treatment or who have already been assessed by a doctor. Because it is the as-labelled 250 strength, it may provide stronger maintenance treatment than lower options, but it is still meant for regular control rather than fast relief. A clinician may select Ibiflo-S 250 Nexhaler when a step-up in controller therapy is appropriate.

• Long-term asthma control
• Prevention of wheezing
• Reduction of shortness of breath
• Decreasing nighttime asthma symptoms
• Maintenance therapy for persistent asthma

• Take Ibiflo-S 250 Nexhaler exactly as prescribed by your doctor.
• Use the tablet only in the way directed for this product; do not crush, split, or chew unless your prescriber/pharmacist has specifically told you to.
• Take it at the same time(s) every day to maintain steady asthma control.
• Do not use Ibiflo-S 250 Nexhaler for sudden asthma attacks; keep a quick-relief inhaler available if prescribed.
• If a dose is missed, take it when remembered unless it is almost time for the next dose; do not double up.
• Follow any food instructions from your prescriber or the package insert, since the tablet form may have specific administration directions.

Each Ibiflo-S 250 Nexhaler tablet provides the labeled 250-strength salmeterol/fluticasone propionate dose as a maintenance controller. How often it is taken and the maximum daily amount depend on the prescriber’s plan, because this higher-strength product is not meant for self-dosing. Your doctor decides the exact schedule based on your asthma severity and response to treatment.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Salmeterol + Fluticasone Propionate may include:

• Throat irritation
• Hoarseness or voice changes
• Headache
• Cough
• Nasal symptoms
• Mild tremor or nervousness

• Ibiflo-S 250 Nexhaler is not a rescue medicine and should not replace a fast-acting inhaler during an asthma attack.
• Because this is the 250-strength product, it should be used only when a doctor has determined that this higher controller dose is appropriate.
• Tell your doctor if you have heart disease, high blood pressure, arrhythmias, diabetes, thyroid disease, seizures, or glaucoma.
• Using too much salmeterol-containing medicine can raise the risk of serious heart-related side effects.
• Long-term inhaled corticosteroid exposure may increase the risk of oral thrush, bone thinning, cataracts, or glaucoma.
• Let your prescriber know if you take strong CYP3A4 inhibitors, since they can raise fluticasone levels.
• If you are pregnant, breastfeeding, or having a severe asthma flare, ask your clinician before using or changing therapy.

• Other long-acting beta agonists or asthma medicines containing salmeterol
• Strong CYP3A4 inhibitors such as ritonavir, cobicistat, ketoconazole, or clarithromycin
• Beta-blockers, including some heart and eye medicines
• Diuretics that can lower potassium
• Other corticosteroids, which may increase steroid-related effects

Store Ibiflo-S 250 Nexhaler in the original strip/box at room temperature, away from moisture, heat, and direct light.