Seretide Diskus 50 mcg/100 mcg Accuhaler

Seretide Diskus 50 mcg/100 mcg Accuhaler is a combination inhalation medicine that contains salmeterol 50 mcg and fluticasone propionate 100 mcg in each dose. It belongs to the long-acting beta2-agonist plus inhaled corticosteroid class and is used as a controller treatment for asthma. This Seretide Diskus 50 mcg/100 mcg Accuhaler is taken by inhalation, not by mouth, and it helps reduce airway swelling while keeping the airways open over time.

How it works: Salmeterol relaxes the muscles around the airways so breathing passages stay open longer, while fluticasone propionate reduces inflammation and swelling inside the lungs. In this Seretide Diskus 50 mcg/100 mcg Accuhaler form, the medicine is inhaled directly into the lungs so it can work where it is needed most.

Seretide Diskus 50 mcg/100 mcg Accuhaler is a lower-dose combination option compared with stronger salmeterol/fluticasone inhaler strengths, so it may be chosen for people whose asthma needs regular controller therapy but not a higher steroid load. Because it is not a rescue medicine, a doctor may select this strength when they want daily maintenance control with a balanced dose of fluticasone propionate and salmeterol.

• Maintenance treatment of asthma
• Long-term control of wheezing
• Prevention of shortness of breath from asthma
• Reducing nighttime asthma symptoms
• Helping lower flare-up risk when used regularly

• Use Seretide Diskus 50 mcg/100 mcg Accuhaler exactly as prescribed; it is an inhaled powder dose, not a tablet to swallow.
• Open the Accuhaler and load one dose only when you are ready to inhale it.
• Breathe out away from the device first, then inhale deeply and steadily through the mouthpiece.
• Do not wash the inside of the Accuhaler; keep it dry and clean the mouthpiece with a dry tissue if needed.
• Rinse your mouth with water and spit after each dose to help reduce the risk of oral thrush.
• Do not use this medicine for sudden asthma attacks; keep a fast-acting rescue inhaler for emergencies.

Each dose of Seretide Diskus 50 mcg/100 mcg Accuhaler delivers salmeterol 50 mcg and fluticasone propionate 100 mcg. It is usually taken twice daily for asthma maintenance, but the exact schedule and whether a different daily amount is appropriate must be decided by the prescriber. Do not exceed the maximum prescribed number of inhalations per day, and do not use extra doses for quick relief unless your doctor specifically instructs you to do so.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Salmeterol + Fluticasone Propionate may include:

• Sore throat
• Hoarseness or voice changes
• Oral thrush (yeast infection in the mouth)
• Headache
• Mild cough after inhalation
• Tremor or shakiness
• Fast or noticeable heartbeat

• Seretide Diskus 50 mcg/100 mcg Accuhaler is for asthma maintenance only and should not be used to treat sudden breathing problems.
• People with heart disease, high blood pressure, arrhythmias, or hyperthyroidism need careful monitoring because salmeterol can affect the heart.
• Long-term or high-dose inhaled steroid use can increase the risk of oral thrush and, in some people, bone or eye problems.
• Tell your doctor if you have diabetes, because fluticasone can sometimes affect blood sugar control.
• Use caution if you have a history of seizures, low potassium, or severe liver disease.
• Do not stop this medicine suddenly without medical advice, especially if you have been using it regularly.
• If symptoms get worse or you need your rescue inhaler more often, contact a clinician promptly.

• Strong CYP3A4 inhibitors such as ketoconazole, itraconazole, clarithromycin, ritonavir, or cobicistat may increase fluticasone exposure.
• Other long-acting beta agonists or asthma medicines containing salmeterol should generally not be used together.
• Beta-blockers can reduce the bronchodilator effect and may worsen asthma.
• Diuretics and some other medicines can increase the risk of low potassium when combined with salmeterol.
• MAO inhibitors or tricyclic antidepressants may increase the risk of cardiovascular side effects.

Store Seretide Diskus 50 mcg/100 mcg Accuhaler in a dry place at room temperature, away from moisture and heat, and keep the device tightly closed until use.