Onglyza 2.5 mg Tablet

Onglyza 2.5 mg Tablet contains 2.5 mg of saxagliptin in each tablet. It belongs to a class of diabetes medicines called DPP-4 inhibitors, which are used along with diet and exercise to help improve blood sugar control in adults with type 2 diabetes. Onglyza 2.5 mg Tablet is not insulin and is not used to treat type 1 diabetes or diabetic ketoacidosis. It is taken by mouth as a tablet.

How it works: Saxagliptin helps your body release more insulin after meals and lowers the amount of sugar made by the liver by supporting the natural incretin system. Because Onglyza 2.5 mg Tablet is an oral tablet, it is taken once it is swallowed and absorbed rather than acting like insulin injections.

Onglyza 2.5 mg Tablet is the lower-strength tablet in the Onglyza line, alongside Onglyza 5 mg Tablet. This 2.5 mg strength may be chosen for people who need a lower dose because of kidney function, drug interactions, or other factors your doctor has assessed. It may have the same type of blood sugar-lowering effect as the 5 mg tablet, but it is meant for patients whose prescribed dose is specifically 2.5 mg.

• Helps improve blood sugar control in adults with type 2 diabetes
• Used with diet and exercise
• May be used alone or with other diabetes medicines
• Not for type 1 diabetes
• Not for diabetic ketoacidosis

• Swallow the Onglyza 2.5 mg Tablet whole with water.
• Take it exactly as prescribed, with or without food.
• Take it at the same time each day if your doctor tells you to use it once daily.
• Do not split, crush, or chew the tablet unless your pharmacist specifically says it is okay.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.
• Continue your diabetes meal plan and activity plan while taking this tablet.

Each Onglyza 2.5 mg Tablet provides 2.5 mg of saxagliptin. The usual frequency is once daily, but your doctor decides the exact dose and schedule based on your kidney function, other medicines, and blood sugar goals. Do not take more than the prescribed daily amount; this strength is specifically intended for the 2.5 mg dose, not for self-adjusting.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Saxagliptin may include:

• Runny or stuffy nose
• Sore throat
• Headache
• Upper respiratory symptoms
• Stomach discomfort
• Diarrhea
• Mild joint pain

• Tell your doctor if you have kidney disease, because the 2.5 mg strength may be selected for reduced kidney function.
• Use caution if you take insulin or a sulfonylurea, since low blood sugar can happen more often with combination therapy.
• Report any history of pancreatitis before starting Onglyza 2.5 mg Tablet.
• Get medical help if you notice swelling, trouble breathing, or sudden weight gain, which may signal heart failure.
• Tell your prescriber about any serious allergy to saxagliptin or similar medicines.
• Use caution when driving or operating machinery if you feel dizzy or weak from low blood sugar.
• Avoid alcohol excess, since it can make blood sugar harder to control.

• Insulin
• Sulfonylureas such as glipizide or glyburide
• Strong CYP3A4/5 inhibitors such as ketoconazole or clarithromycin
• Other diabetes medicines that can lower blood sugar
• Digoxin

Store Onglyza 2.5 mg Tablet at room temperature in the original strip/box, away from moisture and heat.