Onglyza 5 mg Tablet

Onglyza 5 mg Tablet contains 5 mg of saxagliptin in each tablet. It is an oral diabetes medicine in the DPP-4 inhibitor class, used along with diet and exercise to help lower blood sugar in adults with type 2 diabetes. Onglyza 5 mg Tablet is not used to treat type 1 diabetes or diabetic ketoacidosis. This pack contains tablets made by AstraZeneca, India.

How it works: Saxagliptin blocks the DPP-4 enzyme, which helps raise the body’s own incretin hormones after meals. That can lead to more insulin release and less sugar made by the liver, and the Onglyza 5 mg Tablet is the convenient tablet form used by mouth.

Onglyza 5 mg Tablet is the higher sibling strength compared with Onglyza 2.5 mg Tablet, and it is used when a doctor decides the 5 mg dose is appropriate for blood sugar control. Because it is a full-strength tablet, it is not meant for self-adjusting or for anyone who has been told they need a reduced dose, such as some people with kidney problems.

• Type 2 diabetes mellitus
• Blood sugar control with diet and exercise
• Add-on treatment to other diabetes medicines
• Lowering fasting and after-meal glucose
• Diabetes treatment plan directed by a clinician

• Swallow the Onglyza 5 mg Tablet whole with water.
• Take it exactly as prescribed; do not split, crush, or chew the tablet unless your pharmacist specifically says it is acceptable.
• It can be taken with or without food.
• Try to take it at the same time each day to help you remember.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.

Each Onglyza 5 mg Tablet provides 5 mg of saxagliptin, which is a full tablet strength and not the lower 2.5 mg option. The usual dose is one tablet once daily, but your doctor may choose a different plan based on your kidney function, other medicines, and blood sugar goals. Do not take more than the amount your prescriber recommends; the maximum daily dose for this product is typically 5 mg unless your clinician instructs otherwise.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Saxagliptin may include:

• Headache
• Upper respiratory tract symptoms, such as runny nose or sore throat
• Nausea
• Diarrhea
• Urinary tract infection
• Low blood sugar when used with insulin or a sulfonylurea
• Fatigue

• Use caution if you have kidney disease, because the 5 mg tablet may not be the right dose for everyone.
• Tell your doctor if you have heart failure or a history of swelling and shortness of breath.
• Low blood sugar is more likely if Onglyza 5 mg Tablet is taken with insulin or a sulfonylurea.
• Avoid driving or heavy machinery if you feel dizzy or low in blood sugar.
• Alcohol can affect blood sugar control, so ask your clinician how much, if any, is safe for you.
• This tablet is for type 2 diabetes only and should not be used for diabetic ketoacidosis or type 1 diabetes.
• Tell your provider about all medicines and supplements you use before starting this strength.

• Insulin
• Sulfonylureas such as glipizide or glyburide
• Strong CYP3A4/5 inhibitors such as ketoconazole or clarithromycin
• Rifampin, which can reduce saxagliptin levels
• Other diabetes medicines that may increase the risk of low blood sugar

Store Onglyza 5 mg Tablet at room temperature in its original strip or box, protected from moisture and out of reach of children.