Valsac 50 Tablet

Valsac 50 Tablet contains sacubitril and valsartan in each tablet, with a strength of 50 mg as labelled. It belongs to the angiotensin receptor-neprilysin inhibitor (ARNI) class and is used to help treat heart failure, especially to reduce the risk of hospitalization and cardiovascular death in appropriate patients. This tablet is prescription-only and is not meant for self-starting or casual blood pressure use. A doctor uses it when a patient needs a medicine that works on both vessel relaxation and hormone pathways involved in heart strain.

How it works: Sacubitril helps the body keep natural vasodilating peptides active longer, which can relax blood vessels and reduce stress on the heart. Valsartan blocks angiotensin II receptors to lower vessel tightening and fluid-related strain, and the tablet combines both actions in one oral dose.

Valsac 50 Tablet is the 50 mg tablet strength, which is a lower dose than higher-strength sacubitril/valsartan tablets and is often used when a doctor is starting therapy or adjusting treatment upward carefully. It may be chosen for people who need a gentler step-in to treatment, such as those who are more sensitive to blood pressure drops, and the tablet form makes routine daily dosing straightforward. Doctors may select this strength to build toward a target dose over time rather than begin with a stronger tablet right away.

• Chronic heart failure treatment
• Reduce risk of heart failure hospitalization
• Support improved heart function in eligible patients
• Lower strain on the heart and blood vessels

• Swallow Valsac 50 Tablet whole with water; do not crush or chew unless your doctor specifically tells you otherwise.
• Take it at the same time each day to help maintain steady effect.
• It can be taken with or without food.
• If your doctor changes you from an ACE inhibitor, there must usually be a washout period before starting this medicine.
• Do not take extra tablets to make up for a missed dose unless your prescriber instructs you to do so.

Each Valsac 50 Tablet provides sacubitril 50 mg plus valsartan in the labelled amount for this product. The doctor decides how often to take it, but sacubitril/valsartan is commonly taken twice daily and the dose may be increased or adjusted based on blood pressure, kidney function, and tolerance. Do not exceed the prescribed daily maximum; the exact amount is individualized for each patient and this 50 mg tablet is often used as a starting or step-up strength rather than a final dose.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sacubitril + Valsartan may include:

• Low blood pressure or lightheadedness, which may be more noticeable when starting Valsac 50 Tablet
• Dizziness
• Tiredness
• Headache
• Cough
• High potassium on blood tests

• Do not use during pregnancy because medicines that affect the renin-angiotensin system can harm the unborn baby.
• Avoid using this tablet with an ACE inhibitor at the same time, and ask about the required washout period when switching medicines.
• Tell your doctor if you have a history of angioedema, kidney disease, or liver disease before starting Valsac 50 Tablet.
• This medicine can lower blood pressure, so rise slowly from sitting or lying positions and be careful with driving until you know your response.
• Avoid potassium salt substitutes and potassium supplements unless your clinician says they are safe for you.
• Alcohol can add to dizziness or low blood pressure in some people taking this medicine.
• If you are dehydrated from vomiting, diarrhea, or heavy sweating, contact your doctor because this tablet may affect blood pressure and kidney function more strongly.

• ACE inhibitors such as lisinopril, enalapril, or ramipril
• Other blood pressure medicines, especially diuretics, which can increase dizziness or low blood pressure
• Potassium supplements or potassium-sparing diuretics such as spironolactone
• NSAIDs such as ibuprofen or naproxen, which can worsen kidney effects in some patients
• Lithium, because levels may rise and side effects may increase

Store Valsac 50 Tablet in its original strip/box at room temperature, away from moisture, heat, and direct light.