Arnisac 50 Tablet

Arnisac 50 Tablet is a prescription medicine that contains sacubitril 50 mg plus valsartan in each tablet. It belongs to the angiotensin receptor neprilysin inhibitor (ARNI) class and is used to help treat certain types of chronic heart failure and lower the risk of hospitalization and death from heart failure in eligible adults. Arnisac 50 Tablet works on both the heart and blood vessels, so it is not a simple blood pressure pill, although it can also lower blood pressure.

How it works: In tablet form, Arnisac 50 Tablet delivers sacubitril and valsartan together to help the body remove extra salt and water while relaxing blood vessels. Sacubitril helps increase helpful natural substances that widen blood vessels, and valsartan blocks a hormone that tightens them, making it easier for the heart to pump.

Arnisac 50 Tablet is the lower sibling strength of the brand line that also includes Arnisac 100 Tablet. This 50 mg tablet may be chosen when a doctor wants a gentler starting or step-up dose, or when blood pressure, kidney function, age, or prior tolerance suggests starting lower is safer. It is not meant to be swapped on your own for the 100 mg tablet, because the dose is tailored to the individual patient.

• Chronic heart failure in eligible adults
• To reduce the risk of heart failure hospitalization
• To help lower blood pressure in some patients
• Heart and blood vessel support as prescribed by a doctor

• Swallow Arnisac 50 Tablet whole with water; do not crush, chew, or split unless your doctor says it is okay.
• Take it at the same times each day to keep a steady effect.
• You can take it with or without food.
• If it upsets your stomach or causes dizziness, standing up slowly may help.
• If your doctor changes the dose, do not switch to Arnisac 100 Tablet on your own.
• Do not take this tablet at the same time as another medicine containing an ACE inhibitor unless your doctor has given specific instructions.

Each Arnisac 50 Tablet contains sacubitril 50 mg plus valsartan at the labeled strength for this tablet. The dose is usually taken twice daily, but your doctor decides whether Arnisac 50 Tablet is the right starting dose, step-up dose, or maintenance dose for you. Do not exceed the total daily amount your prescriber recommends; the exact maximum depends on your treatment plan and whether you later move to a higher strength such as Arnisac 100 Tablet.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sacubitril + Valsartan may include:

• Low blood pressure or lightheadedness, especially when first starting or increasing the dose
• Dizziness
• High blood potassium
• Cough
• Tiredness
• Kidney function changes
• More frequent lightheadedness may happen in people sensitive to blood pressure drops, including those starting at Arnisac 50 Tablet

• Do not use this medicine during pregnancy; it can harm an unborn baby.
• Tell your doctor if you have a history of angioedema, because this medicine may not be safe for you.
• Avoid taking it with an ACE inhibitor, and do not start or stop these medicines without medical guidance.
• Use caution if you have kidney disease, liver disease, low blood pressure, or dehydration.
• Limit alcohol if it makes you more dizzy or lowers your blood pressure further.
• Be careful when driving or using machinery until you know how Arnisac 50 Tablet affects you.
• Check with your doctor before using salt substitutes or potassium supplements, because this medicine can raise potassium levels.

• ACE inhibitors such as lisinopril or enalapril
• Other ARBs or aliskiren, especially in people with diabetes or kidney disease
• Potassium supplements and potassium-sparing diuretics
• NSAIDs such as ibuprofen or naproxen
• Lithium

Store Arnisac 50 Tablet in its original strip or box at room temperature, away from moisture and excessive heat.