Combitide 25 mcg/125 mcg Inhaler

Combitide 25 mcg/125 mcg Inhaler is a prescription combination inhaler that contains salmeterol 25 mcg and fluticasone propionate 125 mcg in each dose. It belongs to the bronchodilator plus inhaled corticosteroid class and is used for long-term control of asthma symptoms, not for sudden asthma attacks. This specific Combitide 25 mcg/125 mcg Inhaler is a maintenance medicine that helps keep airways open and reduce inflammation over time. The strip/box of 10 inhalers is manufactured by Sun Pharmaceutical Industries Ltd.

How it works: Salmeterol relaxes the muscles around the airways so air can move in and out more easily. Fluticasone propionate is a steroid that lowers swelling and irritation inside the lungs when taken regularly through the inhaler.

Combitide 25 mcg/125 mcg Inhaler is the lower-strength sibling of Combitide 50 mcg/250 mcg Inhaler, so it may be chosen when a doctor wants a smaller steroid and LABA dose. It can suit people whose asthma is being stepped up from a simpler controller or who need a lower maintenance dose than the 50 mcg/250 mcg strength. It is not a rescue inhaler, and its effect is for ongoing control rather than immediate relief.

• Long-term asthma maintenance treatment
• Prevention of wheezing and shortness of breath
• Reducing daytime and nighttime asthma symptoms
• Helping lower flare-up frequency when used regularly

• Use the inhaler exactly as your doctor prescribed; this is a maintenance inhaler, not a quick-relief medicine for sudden attacks.
• Follow the device instructions carefully so you get the full 25 mcg/125 mcg dose from each inhalation.
• If your doctor prescribed more than one inhalation, wait the recommended time between puffs and use it at the same times each day.
• Rinse your mouth with water and spit it out after use to help reduce the risk of oral thrush.
• Do not stop using Combitide 25 mcg/125 mcg Inhaler on your own, even if you feel well, unless your doctor tells you to.
• If you need your rescue inhaler more often than usual, contact your doctor rather than increasing this inhaler on your own.

Each dose of Combitide 25 mcg/125 mcg Inhaler delivers salmeterol 25 mcg plus fluticasone propionate 125 mcg. The exact number of inhalations and how often you use it is determined by your doctor based on asthma control, and this strength is generally used as a regular maintenance dose rather than an as-needed medicine. Do not take more than prescribed, because the maximum daily use depends on your individualized treatment plan and the specific inhaler instructions from your clinician.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Salmeterol + Fluticasone Propionate may include:

• Hoarseness or voice changes
• Throat irritation
• Headache
• Cough after inhalation
• Oral thrush (more likely if you do not rinse your mouth)
• Nasal irritation or runny nose

• Do not use this inhaler for sudden asthma attacks or rapidly worsening breathing problems.
• Tell your doctor if you have heart disease, high blood pressure, an irregular heartbeat, seizures, diabetes, thyroid disease, or low potassium.
• Because this is a higher-maintenance asthma dose than some lower-strength options, use it only as directed and do not increase the dose yourself.
• Rinse and spit after each use to lower the chance of fungal infection in the mouth and throat.
• Let your doctor know if you have ever had tuberculosis, pneumonia, or a weakened immune system.
• Alcohol is not a direct ingredient concern, but heavy drinking may worsen asthma control and increase side effect risk in some people.
• Use caution when driving if you feel shaky, dizzy, or unwell after inhalation.

• Other LABA medicines or bronchodilators used too often
• Strong CYP3A4 inhibitors such as ritonavir, ketoconazole, or clarithromycin
• Beta-blockers such as propranolol, which can reduce the inhaler’s effect
• Diuretics or medicines that can lower potassium
• Other corticosteroids, which may increase steroid-related side effects

Store Combitide 25 mcg/125 mcg Inhaler at room temperature in a dry place, away from moisture, heat, and direct sunlight, and keep the inhaler capped when not in use.