Sitazit-M 50 mg/500 mg Tablet

Sitazit-M 50 mg/500 mg Tablet is a prescription diabetes medicine that combines sitagliptin 50 mg and metformin 500 mg in each tablet. It belongs to the DPP-4 inhibitor and biguanide classes and is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes. The Sitazit-M 50 mg/500 mg Tablet is not for type 1 diabetes or diabetic ketoacidosis. It is taken by mouth as a tablet and is designed for people who need both medicines in one dose.

How it works: Sitagliptin helps raise insulin release after meals and lowers the amount of sugar the liver makes by supporting natural gut hormones. Metformin lowers glucose made by the liver and helps the body use insulin better, and this tablet combines both actions in one oral dose.

Sitazit-M 50 mg/500 mg Tablet is a medium-strength combination tablet, so it may be chosen when a doctor wants the blood sugar benefits of both sitagliptin and a moderate amount of metformin in one pill. Because it contains 500 mg of metformin, it can fit patients who need more than a low starting metformin amount but do not yet need a higher metformin strength in the same tablet. Since there are no other listed strengths or forms in this brand range here, the doctor will individualize how this tablet fits into the overall daily dose.

• Type 2 diabetes blood sugar control
• Added to diet and exercise
• Combination therapy when two medicines are needed
• Helps lower fasting and after-meal glucose
• May be used when a doctor wants one tablet instead of separate medicines

• Swallow the Sitazit-M 50 mg/500 mg Tablet whole with a glass of water; do not crush or chew unless your prescriber specifically says otherwise.
• Take it with food or just after a meal to help reduce stomach upset from metformin.
• Take it at the same time each day to help you remember and keep blood sugar levels steadier.
• Do not take extra tablets to make up for a missed dose if it is almost time for the next dose.
• Follow the exact dosing schedule your doctor gives you, since this combination tablet may be part of a larger diabetes plan.
• If you also use insulin or a sulfonylurea, ask your clinician how to monitor for low blood sugar.

Each Sitazit-M 50 mg/500 mg Tablet provides sitagliptin 50 mg plus metformin 500 mg. It is often taken once daily or twice daily depending on the patient’s blood sugar needs, kidney function, and the rest of the diabetes regimen, and the prescriber decides the exact schedule. The maximum daily amount depends on the doctor’s plan and the other medicines being used, so do not change the dose on your own.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sitagliptin + Metformin may include:

• Diarrhea, which can be more noticeable because this tablet contains metformin 500 mg
• Nausea
• Stomach upset or abdominal pain
• Gas or bloating
• Headache
• Upper respiratory symptoms such as a runny nose or sore throat
• Mild tiredness

• Do not use Sitazit-M 50 mg/500 mg Tablet for type 1 diabetes or diabetic ketoacidosis.
• Tell your doctor if you have kidney disease, because metformin-containing tablets may need dose changes or may not be appropriate.
• Avoid heavy alcohol use, since alcohol can raise the risk of lactic acidosis with metformin.
• Use extra caution if you have a history of pancreatitis.
• Watch for low blood sugar if this tablet is combined with insulin or a sulfonylurea.
• Tell your clinician about liver disease, heart failure, or severe illness before starting treatment.
• If you are scheduled for surgery or an imaging test with contrast dye, ask whether the tablet should be held temporarily.

• Insulin or sulfonylureas, which can increase the risk of low blood sugar
• Alcohol, which can raise the risk of metformin-related lactic acidosis
• Iodinated contrast dye used in some scans, which can affect kidney function and metformin safety
• Certain diuretics or other medicines that may change kidney function or hydration status
• Other diabetes medicines that may require dose adjustment when used together

Store Sitazit-M 50 mg/500 mg Tablet at room temperature in the original strip or box, away from excess heat, moisture, and light.