Stalix M XR 100+500 Tablet

Stalix M XR 100+500 Tablet is a prescription diabetes medicine that contains sitagliptin 100 mg and metformin 500 mg in each tablet. It combines a DPP-4 inhibitor with a biguanide to help lower blood sugar in adults with type 2 diabetes. This strength is used as part of a treatment plan that also includes diet, exercise, and regular glucose checks. Stalix M XR 100+500 Tablet is not for type 1 diabetes or diabetic ketoacidosis.

How it works: Sitagliptin helps the body increase insulin release after meals and lowers the amount of sugar made by the liver by boosting natural incretin hormones. Metformin reduces glucose production in the liver and helps the body use insulin better, and in this tablet both ingredients work together to improve blood sugar control.

Stalix M XR 100+500 Tablet is a higher-strength option because it provides the full sitagliptin 100 mg dose along with metformin 500 mg in one tablet. Compared with Stalix M 50+500 Tablet, it is more likely to be chosen for people whose doctor wants the higher sitagliptin dose and has already assessed that this strength is appropriate. The XR labeling indicates an extended-release form, which may be preferred when once-daily dosing is desired and tolerance has been considered.

• Type 2 diabetes treatment
• Blood sugar control with diet and exercise
• Add-on therapy when one medicine is not enough
• Lowering fasting and after-meal glucose

• Swallow the Stalix M XR 100+500 Tablet whole with water; do not crush, split, or chew it unless your prescriber specifically says otherwise.
• Take it exactly at the time your doctor recommends, often once daily with a meal to help reduce stomach upset.
• Do not take extra tablets to make up for a missed dose unless your prescriber or pharmacist instructs you to do so.
• Check your blood sugar regularly while taking Stalix M XR 100+500 Tablet, since dose needs may change over time.
• Avoid heavy alcohol intake, because metformin can raise the risk of lactic acidosis and blood sugar problems.

Each Stalix M XR 100+500 Tablet provides sitagliptin 100 mg and metformin 500 mg. The usual frequency is once daily for XR products, but the exact schedule and whether this strength is the right fit are decided by the prescriber based on blood sugar, kidney function, and other medicines. Do not exceed the daily amount your doctor prescribes; the tablet strength should match the treatment plan rather than being increased on your own.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sitagliptin + Metformin may include:

• nausea
• diarrhea
• stomach upset or abdominal pain
• gas or bloating
• headache
• cold-like symptoms
• low blood sugar when used with insulin or a sulfonylurea

• This is a higher-strength Stalix M XR tablet, so it should only be used when a clinician has reviewed your current diabetes plan.
• Do not use for type 1 diabetes or diabetic ketoacidosis.
• Kidney function matters with metformin-containing tablets, so your doctor may monitor labs before and during treatment.
• Limit alcohol, because alcohol can increase the risk of lactic acidosis with metformin.
• Use extra caution if you are older, dehydrated, have liver disease, or have a history of pancreatitis.
• If you take insulin or a sulfonylurea, the risk of low blood sugar can be higher.
• Tell your clinician if you are having surgery or imaging with iodinated contrast, since metformin may need to be held temporarily.

• Insulin and sulfonylureas may increase the risk of hypoglycemia.
• Alcohol can raise the risk of metformin-related lactic acidosis.
• Iodinated contrast dye used in some imaging tests may require temporary interruption of metformin.
• Diuretics and other medicines that affect kidney function can increase metformin-related risks.
• Certain drugs that raise blood sugar, such as corticosteroids, may reduce the effectiveness of Stalix M XR 100+500 Tablet.

Store Stalix M XR 100+500 Tablet in its original strip/box at room temperature, away from moisture and excess heat.