Entacom Plus -100 Tablet

Entacom Plus -100 Tablet is a prescription anti-Parkinsonian medicine that contains levodopa, carbidopa, and entacapone in each tablet. It is used to help manage Parkinson’s disease symptoms such as tremor, stiffness, slowness of movement, and “wearing-off” between doses. This exact Entacom Plus -100 Tablet strength is a tablet formulation made by Intas Pharmaceuticals Ltd. and is supplied in a strip/box of 10 tablets.

How it works: In this tablet, levodopa is converted to dopamine in the brain, carbidopa helps more levodopa reach the brain and reduces some side effects, and entacapone slows the breakdown of levodopa so it lasts longer. Taken together, Entacom Plus -100 Tablet helps smooth out movement symptoms and may reduce end-of-dose “off” times.

Entacom Plus -100 Tablet is the only strength sold in our range, so there are no lower or higher sibling strengths to compare with here. Because it is the labeled 100-strength tablet, a doctor may choose it when a patient needs the specific levodopa/carbidopa/entacapone dose combination that best fits their current symptom control and wearing-off pattern.

• Parkinson’s disease symptom control
• Reducing “wearing-off” between levodopa doses
• Tremor and muscle stiffness
• Slowness of movement
• Improving daily movement function

• Swallow the Entacom Plus -100 Tablet whole with water, unless your doctor tells you otherwise.
• Take it exactly at the times prescribed, because timing matters for symptom control.
• If it upsets your stomach, it may be taken with food; keeping the timing consistent can help.
• Do not crush or chew unless a clinician specifically instructs you to do so.
• Avoid high-protein meals right around the dose if your prescriber advises it, since protein can reduce levodopa absorption.
• Do not change the number of tablets or stop Entacom Plus -100 Tablet suddenly without medical advice.

Each Entacom Plus -100 Tablet provides the labeled levodopa + carbidopa + entacapone strength as a single tablet, and the exact schedule depends on the patient’s response. It is often taken several times a day in divided doses; the maximum number of tablets per day is set by the prescribing doctor based on symptom control and tolerability. This is a higher, combination Parkinson’s tablet meant for patients already assessed by a clinician, not a one-size-fits-all starting dose.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Levodopa + Carbidopa + Entacapone may include:

• Nausea
• Dizziness
• Sleepiness or sudden drowsiness
• Diarrhea
• Dry mouth
• Orange-brown urine discoloration
• More nausea or dizziness may happen if the dose is too strong for the patient

• Do not use Entacom Plus -100 Tablet unless your doctor has assessed your Parkinson’s treatment needs.
• It can cause drowsiness or sudden sleep episodes, so avoid driving or operating machinery until you know how it affects you.
• Tell your doctor if you have heart disease, low blood pressure, glaucoma, liver problems, or a history of melanoma.
• Use caution if you drink alcohol, because dizziness and sleepiness can worsen.
• This medicine may darken urine, sweat, or saliva; this is usually harmless but can stain clothing or teeth.
• Older adults may be more sensitive to dizziness, confusion, and movement side effects.
• Do not stop it suddenly, as Parkinson’s symptoms can worsen and withdrawal-like problems can occur.

• MAO inhibitors and certain antidepressants can interact dangerously with levodopa-containing medicines.
• Blood pressure medicines may increase dizziness or fainting.
• Iron supplements can reduce levodopa absorption if taken too close together.
• Other Parkinson’s medicines, including dopamine agonists, may increase side effects or require dose adjustment.
• Certain antipsychotic medicines can reduce the benefit of this tablet.

Store Entacom Plus -100 Tablet in its original strip at room temperature, away from excess heat, moisture, and direct light, and keep it out of reach of children.