Syncapone 50 Tablet

Syncapone 50 Tablet is a prescription anti-Parkinson medicine that combines levodopa, carbidopa, and entacapone in each tablet. It is used to help manage Parkinson’s disease and Parkinson-like symptoms by improving and prolonging the effect of levodopa in the brain. The exact tablet strength is as labelled by the manufacturer, Sun Pharmaceutical Industries Ltd., and it is supplied in strips/boxes of 10 tablets. This combination is typically used when symptoms are not adequately controlled with levodopa alone or when “wearing-off” occurs between doses.

How it works: In this tablet, levodopa is converted into dopamine in the brain, helping improve movement and stiffness. Carbidopa and entacapone help more levodopa reach the brain by reducing its breakdown in the body, so the effect can last longer between doses.

Syncapone 50 Tablet is a combination tablet meant for people whose doctor has already assessed the need for levodopa with carbidopa and entacapone. Compared with the other listed strengths, this tablet provides the same triple-drug approach in a lower labeled strength, which may be preferred when a doctor wants a smaller per-tablet dose or a more gradual adjustment. Because Parkinson’s treatment is individualized, the exact strength chosen depends on symptom control, side effects, and how the patient responds.

• Parkinson’s disease
• Tremor and stiffness from Parkinson’s disease
• Slowness of movement
• “Wearing-off” symptoms between levodopa doses
• Improving daily motor control in selected patients

• Swallow Syncapone 50 Tablet whole with water unless your doctor instructs otherwise.
• Take it at the same times each day to keep symptoms more stable.
• If stomach upset occurs, it may be taken with food, but very high-protein meals can reduce levodopa absorption in some people.
• Do not stop the tablet suddenly without medical advice, as Parkinson’s symptoms can worsen.
• Follow the exact schedule prescribed by your doctor; this tablet is often taken multiple times per day.
• Avoid changing the dose on your own, especially because this combination can cause dose-related side effects.

Each Syncapone 50 Tablet contains the labeled combination dose of levodopa, carbidopa, and entacapone in one tablet. It is often taken several times a day, and the total daily amount is set by the prescriber based on symptom control and tolerability. There is no single maximum that fits everyone, so the doctor decides the schedule and upper limit for the patient.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Levodopa + Carbidopa + Entacapone may include:

• Nausea
• Dizziness or lightheadedness
• Sleepiness
• Diarrhea
• Dry mouth
• Darkened urine or sweat
• Involuntary movements (more likely as levodopa exposure increases)

• This is a prescription Parkinson’s medicine and should be used only under a doctor’s supervision.
• It may cause drowsiness or sudden sleep episodes, so use caution when driving or operating machinery.
• Alcohol can worsen dizziness, sleepiness, and blood pressure effects.
• People with heart disease, liver disease, low blood pressure, or a history of psychiatric illness need careful monitoring.
• Tell your doctor if you have a history of melanoma or suspicious skin lesions.
• This strength may still cause more side effects if the dose is increased too quickly, so titration should be gradual.
• Do not crush or split unless a pharmacist or doctor confirms it is appropriate for your specific tablet.

• MAO inhibitors, especially nonselective MAOIs, can cause dangerous interactions with levodopa combinations.
• Iron supplements may reduce absorption and should be spaced apart if advised by your doctor.
• Antipsychotics and some nausea medicines can interfere with Parkinson’s control.
• Blood pressure medicines may increase dizziness or fainting.
• A high-protein diet may reduce levodopa response in some patients.

Store Syncapone 50 Tablet in the original strip/box at room temperature, away from moisture, heat, and direct light, and keep it out of reach of children.