Entacom Plus - 50 Tablet

Entacom Plus - 50 Tablet is a prescription anti-Parkinsonian medicine that combines levodopa, carbidopa, and entacapone in each tablet. It is used to help manage Parkinson’s disease symptoms such as tremor, stiffness, slowed movement, and “wearing-off” between doses. The 50 Tablet strength is one of the lower labeled strengths in the Entacom Plus range and is intended for patients whose doctor has decided this specific combination and dose are appropriate.

How it works: Levodopa turns into dopamine in the brain, helping improve movement symptoms caused by Parkinson’s disease. Carbidopa helps more levodopa reach the brain and entacapone slows the breakdown of levodopa, so this tablet can help its effect last longer.

Entacom Plus - 50 Tablet is the lower-strength option compared with Entacom Plus -100 Tablet and Entacom Plus -150 Tablet. It may suit people who need a smaller levodopa/carbidopa/entacapone amount per tablet or who are being adjusted carefully to reduce side effects such as nausea, dizziness, or involuntary movements. Doctors may choose this strength when they want more flexible dose titration before moving to higher-strength tablets.

• Parkinson’s disease symptom control
• Reduction of wearing-off episodes
• Improvement in tremor, stiffness, and slowness
• Adjunct treatment when levodopa alone is not enough

• Take Entacom Plus - 50 Tablet exactly as prescribed by your doctor.
• Swallow the tablet whole with water; do not crush, chew, or split it unless your prescriber says it is okay.
• Take it at the same times each day to keep symptoms more stable.
• If it upsets your stomach, ask your doctor whether you can take it with a light snack; high-protein meals may delay or reduce levodopa absorption.
• Avoid suddenly stopping the medicine, because Parkinson’s symptoms can worsen quickly.
• If you miss a dose, follow your prescriber’s instructions; do not double up unless you are told to do so.

Entacom Plus - 50 Tablet provides the labeled lower dose strength in each tablet, and the exact amount you need depends on your treatment plan. It may be taken multiple times a day, but the schedule and maximum daily tablets are individualized by the doctor based on symptom control and side effects. Do not change the dose on your own, because this combination must be adjusted carefully for each patient.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Levodopa + Carbidopa + Entacapone may include:

• nausea
• vomiting
• dizziness
• sleepiness
• dry mouth
• diarrhea
• involuntary movements (dyskinesia), especially if the dose is too high for you

• This is a prescription Parkinson’s medicine and the Entacom Plus - 50 Tablet strength should be used only when a clinician has reviewed your Parkinson’s regimen.
• It can cause dizziness or sleepiness, so use caution when driving or operating machinery until you know how it affects you.
• Alcohol may worsen dizziness, drowsiness, or low blood pressure.
• Use extra caution if you have heart disease, arrhythmias, low blood pressure, glaucoma, liver disease, kidney disease, or a history of hallucinations.
• Tell your doctor about all other Parkinson’s medicines, antidepressants, blood pressure drugs, and supplements before starting Entacom Plus - 50 Tablet.
• Do not take iron supplements or high-iron products at the same time unless your doctor instructs you to do so, because they can interfere with absorption.
• Because higher total daily doses can increase involuntary movements and other side effects, dose increases should be supervised by your doctor.

• MAO inhibitors or recent MAOI use
• other levodopa or carbidopa-containing products
• iron supplements or multivitamins with iron
• blood pressure medicines that can increase dizziness or fainting
• tricyclic antidepressants or other medicines that affect dopamine/serotonin pathways

Store Entacom Plus - 50 Tablet in its original strip/box at room temperature, away from moisture, heat, and direct light.