Entacom Plus -150 Tablet

Entacom Plus -150 Tablet is a prescription anti-Parkinsonian medicine that contains levodopa, carbidopa, and entacapone in each tablet. It is used to help manage Parkinson’s disease symptoms such as tremor, stiffness, slowed movement, and “wearing-off” between levodopa doses. This strength is the Entacom Plus -150 Tablet formulation made by Intas Pharmaceuticals Ltd. and comes as a strip/box of 10 tablets. Because it combines three medicines in one tablet, it is used when a doctor wants more sustained symptom control than levodopa-carbidopa alone.

How it works: In this tablet, levodopa is turned into dopamine in the brain to improve movement, while carbidopa helps more levodopa reach the brain and reduces some side effects outside the brain. Entacapone blocks the breakdown of levodopa, so the effect of each Entacom Plus -150 Tablet can last longer.

Entacom Plus -150 Tablet is a higher-strength option within the Entacom Plus range, alongside Entacom Plus -100 Tablet and Entacom Plus -50 Tablet. A doctor may choose this tablet for people who need stronger symptom relief or who are experiencing wearing-off before the next dose. Since it contains a higher labeled amount per tablet, it is not meant for self-adjustment and should only be used in the schedule prescribed by the clinician.

• Parkinson’s disease
• Stiffness and slowness of movement
• Tremor control
• Wearing-off symptoms between doses
• Motor fluctuations in Parkinson’s disease

• Take Entacom Plus -150 Tablet exactly as prescribed by your doctor and swallow it with water.
• Take it at the same times each day to help keep symptom control steady.
• If it upsets your stomach, ask your doctor or pharmacist whether it should be taken with food; high-protein meals may reduce levodopa absorption.
• Do not crush, split, or chew the tablet unless your prescriber specifically tells you to do so.
• Avoid suddenly stopping the medicine, because Parkinson’s symptoms can worsen quickly.
• Keep track of doses carefully, since this stronger tablet is usually part of a scheduled regimen rather than an as-needed medicine.

Each Entacom Plus -150 Tablet provides the labeled levodopa + carbidopa + entacapone strength for this brand, making it a higher-strength tablet than the Entacom Plus -100 Tablet and Entacom Plus -50 Tablet options. The exact number of tablets per day varies widely based on your prior levodopa response, symptom timing, and tolerability, and your doctor may adjust the dosing interval during treatment. The maximum daily amount depends on the full prescribed regimen and should not be exceeded without medical advice.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Levodopa + Carbidopa + Entacapone may include:

• Nausea
• Dizziness or lightheadedness
• Sleepiness
• Diarrhea
• Dry mouth
• Trouble sleeping
• More noticeable side effects if this higher-strength tablet is started too quickly

• Use caution if you have heart disease, abnormal heartbeat, low blood pressure, liver disease, kidney disease, glaucoma, or a history of ulcers.
• This higher-strength tablet can cause dizziness or sleepiness, so be careful with driving or operating machinery until you know how it affects you.
• Alcohol can worsen dizziness, drowsiness, and blood pressure changes.
• Do not stop Entacom Plus -150 Tablet suddenly unless your doctor tells you to do so.
• Tell your clinician if you have a history of hallucinations, severe confusion, or impulsive behavior.
• Levodopa-containing medicines can darken urine, saliva, or sweat; this is usually harmless but can stain clothing.
• If you are pregnant, planning pregnancy, or breastfeeding, discuss risks and benefits with your prescriber.

• Nonselective MAO inhibitors and recent MAOI use
• Iron supplements or multivitamins with iron
• Antipsychotics or other dopamine-blocking medicines
• Blood pressure medicines that can increase dizziness or fainting
• High-protein meals that may reduce levodopa effect

Store Entacom Plus -150 Tablet in its original strip at room temperature, away from excess heat, moisture, and direct light, and keep it out of reach of children.