Syncapone 150 Tablet

Syncapone 150 Tablet is a prescription anti-Parkinson medicine used to help control symptoms of Parkinson’s disease and parkinsonism, such as tremor, stiffness, and slow movement. Each Syncapone 150 Tablet contains levodopa, carbidopa, and entacapone in the labeled strength, combining three medicines in one tablet. It belongs to the antiparkinsonian drug class and is used when a doctor wants stronger, more sustained symptom control than levodopa alone can provide. This tablet is made by Sun Pharmaceutical Industries Ltd. and comes in strips/boxes of 10 tablets.

How it works: Levodopa turns into dopamine in the brain, helping improve movement, while carbidopa helps more levodopa reach the brain and reduces some side effects like nausea. Entacapone helps levodopa last longer in the body, so this Syncapone 150 Tablet can give more continuous symptom relief between doses.

Syncapone 150 Tablet is a higher-strength tablet in this brand line, so it is usually chosen for people whose symptoms are not adequately controlled with lower strengths such as Syncapone 50 Tablet or Syncapone 100 Tablet. Because it contains all three ingredients at a higher labeled strength, a doctor may use it to reduce “wearing off” between doses and improve day-to-day movement control. It is not meant for self-adjustment or for people who have not already been assessed for levodopa-based therapy.

• Parkinson’s disease symptom control
• Tremor and muscle stiffness
• Slowness of movement
• “Wearing-off” symptoms between levodopa doses
• Parkinsonism as prescribed by a doctor

• Swallow the Syncapone 150 Tablet whole with water unless your doctor tells you otherwise.
• Take it exactly at the times prescribed, because timing matters for symptom control.
• If it upsets your stomach, it may be taken with food; however, high-protein meals can reduce levodopa absorption in some people.
• Do not stop taking Syncapone 150 Tablet suddenly without medical advice.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose; do not double up.
• Follow the same dosing schedule each day to help prevent fluctuations in symptom control.

Each Syncapone 150 Tablet provides the labeled fixed dose of levodopa, carbidopa, and entacapone in one tablet. Because this is a higher-strength formulation, it may be taken multiple times per day in divided doses, but the exact schedule and maximum daily amount must be set by the prescriber based on your response and tolerability. Do not increase the number of tablets on your own, since total daily levodopa exposure and side effects can rise quickly with this strength.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Levodopa + Carbidopa + Entacapone may include:

• Nausea
• Dizziness or lightheadedness
• Sleepiness
• Diarrhea
• Dry mouth
• Abnormal or vivid dreams
• Dyskinesia or extra involuntary movements, which may be more likely with a higher-strength tablet

• Syncapone 150 Tablet is a higher-strength product and should only be used when a clinician has already assessed the need for this levodopa-based combination.
• It can cause sleepiness or sudden sleep episodes, so use caution when driving or operating machinery.
• Alcohol can worsen dizziness, drowsiness, and blood pressure drops.
• Tell your doctor if you have a history of heart disease, low blood pressure, glaucoma, liver problems, kidney problems, or mental health conditions.
• This medicine may cause or worsen involuntary movements, especially if the dose is too high.
• Do not use it with nonselective MAO inhibitors, and tell your prescriber about all antidepressants and Parkinson medicines you take.
• Standing up quickly may cause dizziness or fainting, so rise slowly from sitting or lying positions.

• Nonselective MAO inhibitors such as phenelzine or tranylcypromine
• Iron supplements, which can reduce levodopa absorption
• Dopamine-blocking medicines such as certain antipsychotics or metoclopramide
• Blood pressure medicines, which may add to dizziness or fainting
• Other Parkinson medicines containing levodopa, carbidopa, or entacapone

Store Syncapone 150 Tablet in its original strip/box at room temperature, away from moisture, heat, and direct light, and keep it out of reach of children.