Mymarda 97 mg/103 mg Tablet

Mymarda 97 mg/103 mg Tablet is a prescription medicine that contains sacubitril 97 mg and valsartan 103 mg in each tablet. It belongs to the angiotensin receptor-neprilysin inhibitor (ARNI) class and is used to help treat chronic heart failure and reduce the risk of hospitalization and death in appropriate patients. This Mymarda 97 mg/103 mg Tablet is a higher-strength tablet, so it is meant for patients whose doctor has already evaluated their heart condition and determined this dose is appropriate. It is often used as part of a long-term treatment plan along with other heart medicines and lifestyle measures.

How it works: Sacubitril helps the body keep helpful blood vessel-relaxing substances around longer, while valsartan blocks a hormone that tightens blood vessels and makes the heart work harder. Together in this tablet, they help blood vessels relax, lower strain on the heart, and improve heart failure symptoms over time.

Mymarda 97 mg/103 mg Tablet is the higher-strength version compared with Mymarda 24 mg/26 mg Tablet. Doctors may choose this strength after a patient has tolerated lower doses and needs a stronger maintenance dose for heart failure management. Because it contains more sacubitril and valsartan per tablet, it is not a starting dose for most patients and may have a greater chance of causing low blood pressure or dizziness if used too early.

• Chronic heart failure treatment
• Reduce heart failure hospitalizations
• Lower risk of cardiovascular death in selected patients
• Improve symptoms related to reduced heart pumping
• Part of long-term heart failure therapy

• Swallow the Mymarda 97 mg/103 mg Tablet whole with water.
• Take it exactly as prescribed, usually at the same times each day.
• It can be taken with or without food.
• Do not crush, split, or chew the tablet unless your clinician specifically tells you to.
• If you miss a dose, take it when you remember unless it is close to the next dose; do not double up.
• Do not change to this higher-strength tablet on your own without medical guidance.

Each Mymarda 97 mg/103 mg Tablet provides sacubitril 97 mg and valsartan 103 mg per dose. Depending on the treatment plan, it may be taken twice daily, but the exact schedule and whether this higher strength is appropriate are decided by the doctor. The usual maximum total daily amount for this strength is 2 tablets per day unless a prescriber directs otherwise.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sacubitril + Valsartan may include:

• Dizziness, especially after standing up
• Low blood pressure
• Tiredness
• Cough
• Increased blood potassium
• Headache
• Lightheadedness, which may be more noticeable at this higher strength

• This is a higher-strength Mymarda 97 mg/103 mg Tablet, so it should only be used when a doctor has determined lower strengths are no longer appropriate.
• Do not use if you have a history of angioedema related to ACE inhibitors or ARBs, unless your doctor says otherwise after careful review.
• Do not take with an ACE inhibitor; a washout period is required when switching medicines.
• Avoid use during pregnancy because it can harm an unborn baby.
• Tell your doctor if you have kidney disease, liver disease, or a history of low blood pressure.
• Use caution when driving or standing quickly because dizziness can occur, especially with this strength.
• Avoid potassium supplements or salt substitutes unless your clinician approves them.

• ACE inhibitors such as lisinopril or enalapril
• Other ARBs or aliskiren, which may increase risk of kidney problems and low blood pressure
• Potassium supplements and potassium-sparing diuretics such as spironolactone
• NSAIDs like ibuprofen or naproxen, which can worsen kidney function
• Lithium, which may have increased levels and toxicity

Store Mymarda 97 mg/103 mg Tablet in its original strip or box at room temperature, away from excess heat, moisture, and direct light.