Sitason-M 50/500 Tablet

Sitason-M 50/500 Tablet is a prescription diabetes medicine that combines sitagliptin 50 mg and metformin 500 mg in each tablet. It belongs to the DPP-4 inhibitor plus biguanide class and is used to help lower blood sugar in adults with type 2 diabetes. Sitason-M 50/500 Tablet is taken by mouth as a standard tablet, usually along with diet and exercise, to improve glucose control throughout the day.

How it works: Sitagliptin helps your body release more insulin only when blood sugar is high and also lowers the amount of sugar made by the liver indirectly through hormone effects. Metformin in Sitason-M 50/500 Tablet reduces sugar production by the liver and helps your body use insulin better, making the tablet work on blood sugar from two different angles.

Sitason-M 50/500 Tablet is the fixed-dose tablet that provides sitagliptin 50 mg with metformin 500 mg in one dose, which can be useful when a clinician wants both medicines in a simple tablet form. This strength is commonly chosen for people who need combination treatment but do not need a higher metformin amount in a single tablet; a doctor selects it based on your blood sugar pattern, kidney function, and how well you tolerate metformin.

• Type 2 diabetes
• Blood sugar control with diet and exercise
• Combination therapy when one medicine is not enough
• Lowering fasting and after-meal glucose

• Swallow the Sitason-M 50/500 Tablet whole with water; do not crush, chew, or split it unless your prescriber says otherwise.
• Take it with meals to help reduce stomach upset from metformin.
• Take it at the same time each day to keep blood sugar control steady.
• Follow the exact schedule your doctor gives you; this tablet is not for occasional use.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.
• Check your blood sugar regularly as advised, since dose changes depend on response and lab results.

Each Sitason-M 50/500 Tablet contains sitagliptin 50 mg and metformin 500 mg. The tablet may be taken once or twice daily depending on your doctor’s plan, but the total daily amount of metformin and sitagliptin should not exceed what your prescriber has set for you. Because this is a prescription combination strength, your doctor decides whether Sitason-M 50/500 Tablet is the right dose based on your current medicines, kidney function, and glucose readings.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sitagliptin + Metformin may include:

• Diarrhea
• Nausea
• Stomach upset
• Gas or bloating
• Headache
• Runny nose or upper respiratory symptoms
• Low blood sugar when used with other diabetes medicines

• Do not use Sitason-M 50/500 Tablet for type 1 diabetes or diabetic ketoacidosis.
• Tell your doctor if you have kidney disease, because metformin dosing and safety depend on kidney function.
• Alcohol can raise the risk of metformin-related lactic acidosis, especially with heavy drinking.
• Use caution if you have heart failure, liver disease, or dehydration, since these can increase risk of side effects.
• Low blood sugar is more likely if Sitason-M 50/500 Tablet is combined with insulin or a sulfonylurea.
• Report a history of pancreatitis or severe stomach pain before starting treatment.
• The 50/500 strength is a combination tablet, so it is not ideal for people who need a smaller sitagliptin or metformin dose than this tablet provides.

• Insulin and sulfonylureas may increase the risk of low blood sugar.
• Iodinated contrast dye used for some imaging tests may require temporary stopping of metformin.
• Excess alcohol can increase the risk of serious metformin side effects.
• Certain diuretics, steroids, and other medicines that raise blood sugar may reduce effectiveness.
• Other medicines that affect kidney function may increase the risk of metformin-related problems.

Store Sitason-M 50/500 Tablet at room temperature in the original strip or box, away from moisture and heat, and keep it out of reach of children.