Sitacip M 50 mg/500 mg Tablet PR

Sitacip M 50 mg/500 mg Tablet PR is a prescription diabetes medicine that combines sitagliptin 50 mg and metformin 500 mg in each prolonged-release tablet. It belongs to the DPP-4 inhibitor plus biguanide class and is used to help improve blood sugar control in adults with type 2 diabetes. Sitacip M 50 mg/500 mg Tablet PR is not for type 1 diabetes or diabetic ketoacidosis. Because it is a tablet PR, it is designed for scheduled oral use rather than rapid blood sugar relief.

How it works: Sitagliptin helps the body release more insulin when blood sugar is high and lowers the hormone that raises sugar after meals. Metformin helps the liver make less sugar and helps the body use insulin better, and the tablet form lets both medicines be taken together in one dose.

This Sitacip M 50 mg/500 mg Tablet PR contains a moderate metformin dose with sitagliptin 50 mg, so it may suit people who need combination therapy after one medicine alone has not been enough. The prolonged-release tablet is chosen to provide steadier metformin delivery through the day, which may be easier on the stomach than immediate-release tablets for some patients. A doctor may select Sitacip M 50 mg/500 mg Tablet PR when a lower-strength combination is appropriate and gradual dose adjustment is needed.

• Type 2 diabetes blood sugar control
• Add-on treatment when one diabetes medicine is not enough
• Help lower fasting and after-meal glucose
• Combination therapy for adults with type 2 diabetes
• Diabetes management alongside diet and exercise

• Swallow Sitacip M 50 mg/500 mg Tablet PR whole with water; do not crush, chew, or split the tablet.
• Take it with food to help reduce stomach upset, unless your prescriber tells you otherwise.
• Take it at the same time each day to keep blood sugar control steady.
• Do not use extra tablets to make up a missed dose; skip it if it is almost time for the next dose.
• Follow your doctor’s meal plan, exercise plan, and glucose monitoring instructions while using this tablet.

Each Sitacip M 50 mg/500 mg Tablet PR provides sitagliptin 50 mg plus metformin 500 mg. The dosing schedule is set by the doctor based on your kidney function, current medicines, and blood sugar response; it may be taken once daily or as part of a twice-daily regimen depending on the prescription, but the total daily amount should not be increased on your own. Your prescriber decides the safest maximum dose for this strength and whether a different strength or separate medicines are needed.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sitagliptin + Metformin may include:

• Nausea, especially when starting or increasing treatment
• Diarrhea
• Stomach discomfort or abdominal pain
• Gas or bloating
• Headache
• Mild upper respiratory symptoms such as a runny nose or sore throat

• Do not use this tablet for type 1 diabetes or diabetic ketoacidosis.
• Tell your doctor if you have kidney disease, because metformin-containing products may need dose changes or may not be appropriate.
• Avoid heavy alcohol use, which can raise the risk of lactic acidosis with metformin.
• Use caution if you have a history of pancreatitis, gallstones, or severe stomach pain.
• Let your clinician know if you have heart failure, liver disease, or are dehydrated from vomiting or diarrhea.
• If you take insulin or a sulfonylurea, your risk of low blood sugar may be higher.
• Do not drive or use machinery if you feel dizzy or if your blood sugar is too low.

• Insulin and sulfonylureas, which can increase the risk of hypoglycemia
• Alcohol, which can increase the risk of serious metformin-related side effects
• Iodinated contrast dye used in some imaging tests, which may require temporary stopping
• Certain diuretics, steroids, and other medicines that can raise blood sugar or affect kidneys

Store Sitacip M 50 mg/500 mg Tablet PR in its original strip/box at room temperature, away from moisture, heat, and light.