Sitalembic M 50 mg/500 mg Tablet

Sitalembic M 50 mg/500 mg Tablet is a prescription diabetes medicine that combines sitagliptin 50 mg and metformin 500 mg in each tablet. It belongs to the DPP-4 inhibitor plus biguanide class and is used with diet and exercise to help lower blood sugar in adults with type 2 diabetes. This Sitalembic M 50 mg/500 mg Tablet is not for type 1 diabetes or diabetic ketoacidosis. It is made by Alembic Pharmaceuticals, India, and comes as a strip/box of 10 tablets.

How it works: In this tablet, sitagliptin helps the body release more insulin after meals and lowers the hormone signals that raise blood sugar. Metformin lowers sugar made by the liver and helps the body use insulin better, so the two ingredients work together to improve glucose control.

Sitalembic M 50 mg/500 mg Tablet is a mid-dose combination tablet, so it is typically chosen for people who need both sitagliptin and metformin in one pill but do not need a higher metformin amount. Compared with lower-strength tablets, this 50 mg/500 mg tablet provides the standard sitagliptin amount with a moderate metformin dose, which may be easier on the stomach than stronger metformin combinations for some patients. A doctor may choose this strength when blood sugar remains above target on metformin alone or when a combined tablet is preferred for convenience.

• Type 2 diabetes blood sugar control
• Add-on treatment when metformin alone is not enough
• Combination therapy to simplify diabetes medicines
• Use with diet and exercise
• Lowering fasting and after-meal blood sugar

• Swallow Sitalembic M 50 mg/500 mg Tablet whole with water.
• Take it with food to reduce stomach upset from metformin.
• Take it exactly at the time your doctor prescribes; many patients take it once daily or twice daily depending on the full regimen.
• Do not crush, chew, or split the tablet unless your prescriber or pharmacist specifically says it is safe.
• Keep taking it regularly even if you feel well, because diabetes often has no symptoms.
• Follow your meal plan, activity plan, and home glucose checks while using this tablet.

Each Sitalembic M 50 mg/500 mg Tablet contains sitagliptin 50 mg and metformin 500 mg. The dose may be taken once daily or in divided doses depending on your doctor’s plan, but the exact schedule must be individualized based on your blood sugar, kidney function, and response to treatment. Do not exceed the maximum daily amounts of the ingredients your prescriber sets for you.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sitagliptin + Metformin may include:

• Diarrhea, which is common with metformin and may be more noticeable when starting
• Nausea
• Stomach upset or abdominal pain
• Gas or bloating
• Headache
• Upper respiratory symptoms such as a stuffy nose or sore throat
• Low blood sugar when used with insulin or sulfonylureas

• Sitalembic M 50 mg/500 mg Tablet is for type 2 diabetes only and should not be used for diabetic ketoacidosis or type 1 diabetes.
• Metformin-containing tablets can raise the risk of lactic acidosis, especially if you have kidney disease, severe dehydration, or major infection.
• Tell your doctor if you drink alcohol, because heavy alcohol use increases the risk of lactic acidosis.
• Use caution if you have a history of pancreatitis, heart failure, liver disease, or low vitamin B12.
• This medicine may cause low blood sugar when combined with insulin or certain other diabetes drugs, so watch for shakiness, sweating, or confusion.
• Do not drive or use machinery if you feel dizzy or your blood sugar is low.
• Your doctor may check kidney function before and during treatment with Sitalembic M 50 mg/500 mg Tablet.

• Insulin and sulfonylureas, which can increase the risk of hypoglycemia
• Alcohol, which can increase metformin-related safety risks
• Iodinated contrast dye used for some imaging tests, which may require temporary stopping of metformin
• Certain diuretics, steroids, and other medicines that can affect blood sugar
• Other products containing metformin or sitagliptin, which can lead to duplicate therapy

Store Sitalembic M 50 mg/500 mg Tablet in its original strip at room temperature, away from moisture and excessive heat.