Lupisit M 50 mg/500 mg Tablet

Lupisit M 50 mg/500 mg Tablet is a prescription diabetes medicine that combines sitagliptin 50 mg and metformin 500 mg in each tablet. It belongs to the DPP-4 inhibitor plus biguanide combination class and is used along with diet and exercise to help improve blood sugar control in adults with type 2 diabetes. This Lupisit M 50 mg/500 mg Tablet is not for type 1 diabetes or diabetic ketoacidosis. It is made by Lupin, India, and comes as a tablet in a strip/box of 10.

How it works: Sitagliptin helps the body release more insulin after meals and lowers the amount of sugar made by the liver. Metformin reduces sugar production in the liver and helps the body respond better to insulin, and the tablet form lets both medicines be taken together in one dose.

Lupisit M 50 mg/500 mg Tablet is a mid-strength combination tablet, giving a full 50 mg sitagliptin dose with a moderate 500 mg metformin dose in one pill. Since there are no other Lupisit M strengths or forms listed here, this exact tablet is meant for adults whose doctor wants both medicines together in a single tablet to simplify treatment and improve adherence. It may be chosen when a lower metformin-only approach is not enough, but the prescriber wants to avoid jumping to a higher metformin amount right away.

• Type 2 diabetes blood sugar control
• Used with diet and exercise
• May help lower fasting and after-meal glucose
• Combination therapy when one medicine is not enough

• Swallow the tablet whole with water; do not crush, split, or chew unless your doctor specifically tells you to.
• Take it exactly as prescribed, usually with food or just after a meal if stomach upset occurs.
• Take it at the same time each day to help keep blood sugar control steady.
• Do not take extra tablets to make up for a missed dose; follow your prescriber’s instructions.
• If you have nausea or diarrhea, taking Lupisit M 50 mg/500 mg Tablet with meals may help reduce stomach upset.
• Check your blood sugar as advised, because this tablet works best when paired with diet, exercise, and monitoring.

Each Lupisit M 50 mg/500 mg Tablet contains sitagliptin 50 mg plus metformin 500 mg. The dose is usually taken once or twice daily depending on the patient’s kidney function, blood sugar needs, and how well the medicine is tolerated, and the prescriber decides the exact schedule. The maximum daily amount must be set by the doctor; do not increase the number of tablets on your own.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Sitagliptin + Metformin may include:

• Nausea
• Diarrhea
• Stomach upset
• Gas or bloating
• Headache
• Cold-like symptoms or runny nose
• Low blood sugar if used with insulin or a sulfonylurea

• Lupisit M 50 mg/500 mg Tablet is a higher-combination diabetes tablet and should be used only if your doctor has checked that this strength is appropriate for you.
• Metformin can rarely cause lactic acidosis, and the risk is higher if you have kidney disease, dehydration, severe infection, low oxygen, or heavy alcohol use.
• Tell your doctor if you have ever had pancreatitis, gallstones, or significant abdominal pain before starting this tablet.
• Use caution if you drive or operate machinery, especially if you get low blood sugar when this tablet is combined with insulin or another diabetes medicine.
• Do not use during a severe illness, vomiting, or dehydration without medical advice, because kidney stress can increase metformin risk.
• Let your clinician know about heart disease, liver disease, or planned contrast imaging studies before taking Lupisit M 50 mg/500 mg Tablet.
• Alcohol can raise the risk of lactic acidosis and can also worsen blood sugar swings.

• Insulin and sulfonylureas can increase the risk of low blood sugar.
• Alcohol may increase the risk of metformin-related lactic acidosis.
• Iodinated contrast dye used for some CT scans or X-rays may require temporarily stopping metformin-containing medicine.
• Certain kidney-affecting drugs, including some diuretics, can raise metformin risk if dehydration occurs.
• Rifampin and some other medicines may change blood sugar control and require monitoring.

Store Lupisit M 50 mg/500 mg Tablet at room temperature in the original strip or box, away from excess moisture, heat, and direct light.